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Antibiotic administration exacerbates acute graft vs. host disease-induced bone marrow and spleen damage in lymphopenic mice

BACKGROUND: Hematopoietic stem cell transplantation is a potential cure for certain life-threatening malignant and nonmalignant diseases. However, experimental and clinical studies have demonstrated that pre-transplant myeloablative conditioning damages the gut leading to translocation of intestinal...

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Detalles Bibliográficos
Autores principales: McDaniel Mims, Brianyell, Enriquez, Josue, Pires dos Santos, Andrea, Jones-Hall, Yava, Dowd, Scot, Furr, Kathryn L., Grisham, Matthew B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8346256/
https://www.ncbi.nlm.nih.gov/pubmed/34358240
http://dx.doi.org/10.1371/journal.pone.0254845