BDNF produced by cerebral microglia promotes cortical plasticity and pain hypersensitivity after peripheral nerve injury

Peripheral nerve injury–induced mechanical allodynia is often accompanied by abnormalities in the higher cortical regions, yet the mechanisms underlying such maladaptive cortical plasticity remain unclear. Here, we show that in male mice, structural and functional changes in the primary somatosensor...

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Detalles Bibliográficos
Autores principales: Huang, Lianyan, Jin, Jianhua, Chen, Kai, You, Sikun, Zhang, Hongyang, Sideris, Alexandra, Norcini, Monica, Recio-Pinto, Esperanza, Wang, Jing, Gan, Wen-Biao, Yang, Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8346290/
https://www.ncbi.nlm.nih.gov/pubmed/34292944
http://dx.doi.org/10.1371/journal.pbio.3001337

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