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Severe bowel complications in SARS-CoV-2 patients receiving protocolized care()
INTRODUCTION AND AIMS: A case series of ten patients that received protocolized care for SARS-CoV-2 infection and developed severe gastrointestinal complications, is presented. The aim of our study was to contribute to the ongoing discussion regarding gastrointestinal complications related to SARS-C...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Asociación Mexicana de Gastroenterología. Published by Masson Doyma México S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8346336/ https://www.ncbi.nlm.nih.gov/pubmed/34400118 http://dx.doi.org/10.1016/j.rgmxen.2021.08.009 |
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author | Estevez-Cerda, S.C. Saldaña-Rodríguez, J.A. Alam-Gidi, A.G. Riojas-Garza, A. Rodarte-Shade, M. Velazco-de la Garza, J. Leyva-Alvizo, A. Gonzalez-Ruvalcaba, R. Martinez-Resendez, M.F. Ortiz de Elguea-Lizarraga, J.I. |
author_facet | Estevez-Cerda, S.C. Saldaña-Rodríguez, J.A. Alam-Gidi, A.G. Riojas-Garza, A. Rodarte-Shade, M. Velazco-de la Garza, J. Leyva-Alvizo, A. Gonzalez-Ruvalcaba, R. Martinez-Resendez, M.F. Ortiz de Elguea-Lizarraga, J.I. |
author_sort | Estevez-Cerda, S.C. |
collection | PubMed |
description | INTRODUCTION AND AIMS: A case series of ten patients that received protocolized care for SARS-CoV-2 infection and developed severe gastrointestinal complications, is presented. The aim of our study was to contribute to the ongoing discussion regarding gastrointestinal complications related to SARS-CoV-2 infection. After reviewing the current literature, ours appears to be the first detailed case series on the topic. MATERIALS AND METHODS: A retrospective filtered search of all patients admitted to our hospital for SARS-CoV-2 infection, who developed severe gastrointestinal complications, was performed. All relevant data on hospital patient management, before and after surgery, were collected from the medical records. RESULTS: Of the 905 patients admitted to our hospital due to SARS-CoV-2 infection, as of August 26, 2020, ten of them developed severe gastrointestinal complications. Seven of those patients were men. There were four cases of perforation of the proximal jejunum, three cases of perforations of the ascending colon, one case of concomitant perforation of the sigmoid colon and terminal ileum, one case of massive intestinal necrosis, and one preoperative death. Three right colectomies, four intestinal resections, one Hartmann’s procedure with bowel resection, and one primary repair of the small bowel were performed. The mortality rate of the patients analyzed was 50%. CONCLUSION: Spontaneous bowel perforations and acute mesenteric ischemia are emerging as severe, life-threatening complications in hospitalized SARS-CoV-2 patients. More evidence is needed to identify risk factors, establish preventive measures, and analyze possible adverse effects of the current treatment protocols. |
format | Online Article Text |
id | pubmed-8346336 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Asociación Mexicana de Gastroenterología. Published by Masson Doyma México S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-83463362021-08-09 Severe bowel complications in SARS-CoV-2 patients receiving protocolized care() Estevez-Cerda, S.C. Saldaña-Rodríguez, J.A. Alam-Gidi, A.G. Riojas-Garza, A. Rodarte-Shade, M. Velazco-de la Garza, J. Leyva-Alvizo, A. Gonzalez-Ruvalcaba, R. Martinez-Resendez, M.F. Ortiz de Elguea-Lizarraga, J.I. Rev Gastroenterol Mex (Engl Ed) Special article COVID19 INTRODUCTION AND AIMS: A case series of ten patients that received protocolized care for SARS-CoV-2 infection and developed severe gastrointestinal complications, is presented. The aim of our study was to contribute to the ongoing discussion regarding gastrointestinal complications related to SARS-CoV-2 infection. After reviewing the current literature, ours appears to be the first detailed case series on the topic. MATERIALS AND METHODS: A retrospective filtered search of all patients admitted to our hospital for SARS-CoV-2 infection, who developed severe gastrointestinal complications, was performed. All relevant data on hospital patient management, before and after surgery, were collected from the medical records. RESULTS: Of the 905 patients admitted to our hospital due to SARS-CoV-2 infection, as of August 26, 2020, ten of them developed severe gastrointestinal complications. Seven of those patients were men. There were four cases of perforation of the proximal jejunum, three cases of perforations of the ascending colon, one case of concomitant perforation of the sigmoid colon and terminal ileum, one case of massive intestinal necrosis, and one preoperative death. Three right colectomies, four intestinal resections, one Hartmann’s procedure with bowel resection, and one primary repair of the small bowel were performed. The mortality rate of the patients analyzed was 50%. CONCLUSION: Spontaneous bowel perforations and acute mesenteric ischemia are emerging as severe, life-threatening complications in hospitalized SARS-CoV-2 patients. More evidence is needed to identify risk factors, establish preventive measures, and analyze possible adverse effects of the current treatment protocols. Asociación Mexicana de Gastroenterología. Published by Masson Doyma México S.A. 2021 2021-08-07 /pmc/articles/PMC8346336/ /pubmed/34400118 http://dx.doi.org/10.1016/j.rgmxen.2021.08.009 Text en © 2021 Asociación Mexicana de Gastroenterología. Published by Masson Doyma México S.A. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Special article COVID19 Estevez-Cerda, S.C. Saldaña-Rodríguez, J.A. Alam-Gidi, A.G. Riojas-Garza, A. Rodarte-Shade, M. Velazco-de la Garza, J. Leyva-Alvizo, A. Gonzalez-Ruvalcaba, R. Martinez-Resendez, M.F. Ortiz de Elguea-Lizarraga, J.I. Severe bowel complications in SARS-CoV-2 patients receiving protocolized care() |
title | Severe bowel complications in SARS-CoV-2 patients receiving protocolized care() |
title_full | Severe bowel complications in SARS-CoV-2 patients receiving protocolized care() |
title_fullStr | Severe bowel complications in SARS-CoV-2 patients receiving protocolized care() |
title_full_unstemmed | Severe bowel complications in SARS-CoV-2 patients receiving protocolized care() |
title_short | Severe bowel complications in SARS-CoV-2 patients receiving protocolized care() |
title_sort | severe bowel complications in sars-cov-2 patients receiving protocolized care() |
topic | Special article COVID19 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8346336/ https://www.ncbi.nlm.nih.gov/pubmed/34400118 http://dx.doi.org/10.1016/j.rgmxen.2021.08.009 |
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