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refineR: A Novel Algorithm for Reference Interval Estimation from Real-World Data
Reference intervals are essential for the interpretation of laboratory test results in medicine. We propose a novel indirect approach to estimate reference intervals from real-world data as an alternative to direct methods, which require samples from healthy individuals. The presented refineR algori...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8346497/ https://www.ncbi.nlm.nih.gov/pubmed/34362961 http://dx.doi.org/10.1038/s41598-021-95301-2 |