Cargando…
E2F1 and epigenetic modifiers orchestrate breast cancer progression by regulating oxygen-dependent ESRP1 expression
Epithelial splicing regulatory protein 1 (ESRP1) is an RNA binding protein that governs the alternative splicing events related to epithelial phenotypes. ESRP1 contributes significantly at different stages of cancer progression. ESRP1 expression is substantially elevated in carcinoma in situ compare...
Autores principales: | Ashok, Cheemala, Ahuja, Neha, Natua, Subhashis, Mishra, Jharna, Samaiya, Atul, Shukla, Sanjeev |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8346533/ https://www.ncbi.nlm.nih.gov/pubmed/34362878 http://dx.doi.org/10.1038/s41389-021-00347-6 |
Ejemplares similares
-
Hypoxia-induced TGF-β–RBFOX2–ESRP1 axis regulates human MENA alternative splicing and promotes EMT in breast cancer
por: Ahuja, Neha, et al.
Publicado: (2020) -
Oncometabolite lactate enhances breast cancer progression by orchestrating histone lactylation-dependent c-Myc expression
por: Pandkar, Madhura R., et al.
Publicado: (2023) -
Hypoxia-induced loss of SRSF2-dependent DNA methylation promotes CTCF-mediated alternative splicing of VEGFA in breast cancer
por: Yadav, Pooja, et al.
Publicado: (2023) -
The splicing regulators Esrp1 and Esrp2 direct an epithelial splicing program essential for mammalian development
por: Bebee, Thomas W, et al.
Publicado: (2015) -
Epithelial splicing regulatory protein 1 and 2 (ESRP1 and ESRP2) upregulation predicts poor prognosis in prostate cancer
por: Freytag, Morton, et al.
Publicado: (2020)