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Insights into non-autoimmune type 1 diabetes with 13 novel loci in low polygenic risk score patients

With polygenic risk score (PRS) for autoimmune type 1 diabetes (T1D), this study identified T1D cases with low T1D PRS and searched for susceptibility loci in these cases. Our hypothesis is that genetic effects (likely mediated by relatively rare genetic variants) of non-mainstream (or non-autoimmun...

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Detalles Bibliográficos
Autores principales:	Qu, Jingchun, Qu, Hui-Qi, Bradfield, Jonathan P., Glessner, Joseph T., Chang, Xiao, Tian, Lifeng, March, Michael, Connolly, John J., Roizen, Jeffrey D., Sleiman, Patrick M. A., Hakonarson, Hakon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8346538/ https://www.ncbi.nlm.nih.gov/pubmed/34362956 http://dx.doi.org/10.1038/s41598-021-94994-9

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