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Two rare cases of bronchus‐associated lymphoid tissue lymphoma successfully treated with rituximab‐bendamustine

BALT lymphoma is a rare B‐NHL with a favorable prognosis. We here report on two patients with nonspecific symptoms: one showed as major symptom severe thrombocytopenia and the other dyspnea and dry cough, thereby suggesting an inflammatory focus in the lungs. There is no standard of care established...

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Autores principales: Panitz, Nydia, Gerhardt, Kristin, Becker, Cornelia, Schleife, Hendrikje, Bach, Enrica, Opitz, Sabine, Schaudinn, Alexander, Platzbecker, Uwe, Kayser, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8346601/
https://www.ncbi.nlm.nih.gov/pubmed/34401153
http://dx.doi.org/10.1002/ccr3.4557
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author Panitz, Nydia
Gerhardt, Kristin
Becker, Cornelia
Schleife, Hendrikje
Bach, Enrica
Opitz, Sabine
Schaudinn, Alexander
Platzbecker, Uwe
Kayser, Sabine
author_facet Panitz, Nydia
Gerhardt, Kristin
Becker, Cornelia
Schleife, Hendrikje
Bach, Enrica
Opitz, Sabine
Schaudinn, Alexander
Platzbecker, Uwe
Kayser, Sabine
author_sort Panitz, Nydia
collection PubMed
description BALT lymphoma is a rare B‐NHL with a favorable prognosis. We here report on two patients with nonspecific symptoms: one showed as major symptom severe thrombocytopenia and the other dyspnea and dry cough, thereby suggesting an inflammatory focus in the lungs. There is no standard of care established yet. Both patients were successfully treated with rituximab and bendamustine. Thus, combined immunochemotherapy should be considered as first‐line therapy as in other MALT lymphomas, if the treatment/eradication of an underlying chronic inflammatory disorder/trigger factor can be excluded.
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spelling pubmed-83466012021-08-15 Two rare cases of bronchus‐associated lymphoid tissue lymphoma successfully treated with rituximab‐bendamustine Panitz, Nydia Gerhardt, Kristin Becker, Cornelia Schleife, Hendrikje Bach, Enrica Opitz, Sabine Schaudinn, Alexander Platzbecker, Uwe Kayser, Sabine Clin Case Rep Case Report BALT lymphoma is a rare B‐NHL with a favorable prognosis. We here report on two patients with nonspecific symptoms: one showed as major symptom severe thrombocytopenia and the other dyspnea and dry cough, thereby suggesting an inflammatory focus in the lungs. There is no standard of care established yet. Both patients were successfully treated with rituximab and bendamustine. Thus, combined immunochemotherapy should be considered as first‐line therapy as in other MALT lymphomas, if the treatment/eradication of an underlying chronic inflammatory disorder/trigger factor can be excluded. John Wiley and Sons Inc. 2021-08-06 /pmc/articles/PMC8346601/ /pubmed/34401153 http://dx.doi.org/10.1002/ccr3.4557 Text en © 2021 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Case Report
Panitz, Nydia
Gerhardt, Kristin
Becker, Cornelia
Schleife, Hendrikje
Bach, Enrica
Opitz, Sabine
Schaudinn, Alexander
Platzbecker, Uwe
Kayser, Sabine
Two rare cases of bronchus‐associated lymphoid tissue lymphoma successfully treated with rituximab‐bendamustine
title Two rare cases of bronchus‐associated lymphoid tissue lymphoma successfully treated with rituximab‐bendamustine
title_full Two rare cases of bronchus‐associated lymphoid tissue lymphoma successfully treated with rituximab‐bendamustine
title_fullStr Two rare cases of bronchus‐associated lymphoid tissue lymphoma successfully treated with rituximab‐bendamustine
title_full_unstemmed Two rare cases of bronchus‐associated lymphoid tissue lymphoma successfully treated with rituximab‐bendamustine
title_short Two rare cases of bronchus‐associated lymphoid tissue lymphoma successfully treated with rituximab‐bendamustine
title_sort two rare cases of bronchus‐associated lymphoid tissue lymphoma successfully treated with rituximab‐bendamustine
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8346601/
https://www.ncbi.nlm.nih.gov/pubmed/34401153
http://dx.doi.org/10.1002/ccr3.4557
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