Dissecting the concordant and disparate roles of NDUFAF3 and NDUFAF4 in mitochondrial complex I biogenesis

Distinct sub-assemblies (modules) of mitochondrial complex I (CI) are assembled with the assistance of CI Assembly Factors (CIAFs) through mechanisms that are incompletely defined. Here, using genetic analyses in Drosophila, we report that when either of the CIAFs – NDUFAF3 or NDUFAF4 – is disrupted...

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Detalles Bibliográficos
Autores principales: Murari, Anjaneyulu, Rhooms, Shauna-Kay, Garcia, Christian, Liu, Tong, Li, Hong, Mishra, Bibhuti, Deshong, Cassie, Owusu-Ansah, Edward
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8346666/
https://www.ncbi.nlm.nih.gov/pubmed/34386730
http://dx.doi.org/10.1016/j.isci.2021.102869

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