UDP-glucose pyrophosphorylase 2, a regulator of glycogen synthesis and glycosylation, is critical for pancreatic cancer growth

UDP-glucose pyrophosphorylase 2 (UGP2), the enzyme that synthesizes uridine diphosphate (UDP)-glucose, rests at the convergence of multiple metabolic pathways, however, the role of UGP2 in tumor maintenance and cancer metabolism remains unclear. Here, we identify an important role for UGP2 in the ma...

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Detalles Bibliográficos
Autores principales: Wolfe, Andrew L., Zhou, Qingwen, Toska, Eneda, Galeas, Jacqueline, Ku, Angel A., Koche, Richard P., Bandyopadhyay, Sourav, Scaltriti, Maurizio, Lebrilla, Carlito B., McCormick, Frank, Kim, Sung Eun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8346792/
https://www.ncbi.nlm.nih.gov/pubmed/34330832
http://dx.doi.org/10.1073/pnas.2103592118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8346792/
https://www.ncbi.nlm.nih.gov/pubmed/34330832
http://dx.doi.org/10.1073/pnas.2103592118

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