Isoconazole and Clemizole Hydrochloride Partially Reverse the Xeroderma Pigmentosum C Phenotype

Xeroderma Pigmentosum protein C (XPC) is involved in recognition and repair of bulky DNA damage such as lesions induced by Ultra Violet (UV) radiation. XPC-mutated cells are, therefore, photosensitive and accumulate UVB-induced pyrimidine dimers leading to increased cancer incidence. Here, we perfor...

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Detalles Bibliográficos
Autores principales: Kobaisi, Farah, Sulpice, Eric, Barette, Caroline, Fayyad, Nour, Fauvarque, Marie-Odile, Badran, Bassam, Fayyad-Kazan, Mohammad, Fayyad-Kazan, Hussein, Gidrol, Xavier, Rachidi, Walid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8346964/
https://www.ncbi.nlm.nih.gov/pubmed/34360928
http://dx.doi.org/10.3390/ijms22158156

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8346964/
https://www.ncbi.nlm.nih.gov/pubmed/34360928
http://dx.doi.org/10.3390/ijms22158156

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