Boosted Pro-Inflammatory Activity in Human PBMCs by Lipopolysaccharide and SARS-CoV-2 Spike Protein Is Regulated by α-1 Antitrypsin †

For the treatment of severe COVID-19, supplementation with human plasma-purified α-1 antitrypsin (AAT) to patients is currently considered. AAT inhibits host proteases that facilitate viral entry and possesses broad anti-inflammatory and immunomodulatory activities. Researchers have demonstrated tha...

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Detalles Bibliográficos
Autores principales: Tumpara, Srinu, Gründing, Anna R., Sivaraman, Kokilavani, Wrenger, Sabine, Olejnicka, Beata, Welte, Tobias, Wurm, Maria J., Pino, Paco, Kiseljak, Divor, Wurm, Florian M., Janciauskiene, Sabina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347018/
https://www.ncbi.nlm.nih.gov/pubmed/34360706
http://dx.doi.org/10.3390/ijms22157941

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347018/
https://www.ncbi.nlm.nih.gov/pubmed/34360706
http://dx.doi.org/10.3390/ijms22157941

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