Cargando…

Zonisamide Therapy Reduces Metabolic Consequences and Diminishes Nonalcoholic Fatty Liver Disease in Patients with Epilepsy

Antiepileptic drugs that can reduce aberrant metabolism are beneficial for patients. Zonisamide (ZNS) is a chemical with antiepileptic and antioxidant activities. Here, we evaluate the efficacy of ZNS therapy on reducing obesity and decreasing risks of vascular diseases and hepatic steatosis. Clinic...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huang, Chi-Ren, Chuang, Hung-Yi, Chen, Nai-Ching, Chen, Shu-Fang, Hsu, Chung-Yao, Chuang, Yao-Chung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347271/ https://www.ncbi.nlm.nih.gov/pubmed/34362163 http://dx.doi.org/10.3390/jcm10153380

Ejemplares similares

Autonomic Dysfunction Contributes to Impairment of Cerebral Autoregulation in Patients with Epilepsy
por: Chen, Shu-Fang, et al.
Publicado: (2021)

Zonisamide in the management of epilepsy in the elderly
por: Romigi, Andrea, et al.
Publicado: (2015)

Long-Term Efficacy and Safety of Zonisamide Monotherapy in Epilepsy Patients
por: Park, Sung-Pa, et al.
Publicado: (2007)

Serum Levels of Brain-Derived Neurotrophic Factor and Insulin-Like Growth Factor 1 Are Associated With Autonomic Dysfunction and Impaired Cerebral Autoregulation in Patients With Epilepsy
por: Chen, Shu-Fang, et al.
Publicado: (2018)

Antithyroid Antibodies Are Implicated in Epileptogenesis of Adult Patients With Epilepsy
por: Tsai, Meng-Han, et al.
Publicado: (2015)

Zonisamide Efficacy as Adjunctive Therapy in Children With Refractory Epilepsy
por: KARIMZADEH, Parvaneh, et al.
Publicado: (2013)

Zonisamide Changes Unilateral Cortical Excitability in Focal Epilepsy Patients
por: Joo, Eun Yeon, et al.
Publicado: (2010)

Efficacy of Zonisamide in Migraineurs with Nonresponse to Topiramate
por: Chung, Jin-Young, et al.
Publicado: (2014)

Resveratrol Promotes Mitochondrial Biogenesis and Protects against Seizure-Induced Neuronal Cell Damage in the Hippocampus Following Status Epilepticus by Activation of the PGC-1α Signaling Pathway
por: Chuang, Yao-Chung, et al.
Publicado: (2019)

Comparative Efficacy of Zonisamide and Pregabalin as an Adjunctive Therapy in Children with Refractory Epilepsy
por: TAGHDIRI, Mohammad Mahdi, et al.
Publicado: (2015)

Risk Factors of Hyperammonemia in Patients With Epilepsy Under Valproic Acid Therapy
por: Tseng, Yu-Lung, et al.
Publicado: (2014)

The metabolic influence of duodenal mucosal resurfacing for nonalcoholic fatty liver disease
por: Chuang, Te-Jung, et al.
Publicado: (2023)

Long-term safety and effectiveness of zonisamide in the treatment of epilepsy: a review of the literature
por: Zaccara, Gaetano, et al.
Publicado: (2009)

Safety and Efficacy of Zonisamide in Patients with Epilepsy: A Post-Marketing Surveillance Study
por: Lee, Hye Jin, et al.
Publicado: (2015)

Zonisamide‐responsive myoclonus in SEMA6B‐associated progressive myoclonic epilepsy
por: Herzog, Rebecca, et al.
Publicado: (2021)

Sirtuin 1 Regulates Mitochondrial Biogenesis and Provides an Endogenous Neuroprotective Mechanism Against Seizure-Induced Neuronal Cell Death in the Hippocampus Following Status Epilepticus
por: Chuang, Yao-Chung, et al.
Publicado: (2019)

Risk of Microangiopathy in Patients with Epilepsy under Long-term Antiepileptic Drug Therapy
por: Chen, Nai-Ching, et al.
Publicado: (2018)

Zonisamide Administration Improves Fatty Acid β-Oxidation in Parkinson’s Disease
por: Ueno, Shin-Ichi, et al.
Publicado: (2018)

Improved Antithrombotic Activity and Diminished Bleeding Side Effect of a PEGylated α(IIb)β(3) Antagonist, Disintegrin
por: Kuo, Yu-Ju, et al.
Publicado: (2020)

Safety and Effectiveness of Rosiglitazone in Type 2 Diabetes Patients with Nonalcoholic Fatty Liver Disease
por: Wang, Chao-Hung, et al.
Publicado: (2006)

Clinical significance of serological biomarkers and neuropsychological performances in patients with temporal lobe epilepsy
por: Chang, Chiung-Chih, et al.
Publicado: (2012)

Distal renal tubular acidosis and lethargy associated with zonisamide treatment in a dog with idiopathic epilepsy
por: Itoi, Takamasa, et al.
Publicado: (2022)

Evaluation of antiseizure medications including zonisamide in feline idiopathic epilepsy at a referral hospital in Japan
por: Yoshida, Shino, et al.
Publicado: (2023)

Grounding the Body Improves Sleep Quality in Patients with Mild Alzheimer’s Disease: A Pilot Study
por: Lin, Chien-Hung, et al.
Publicado: (2022)

Correction: Lin et al. Grounding the Body Improves Sleep Quality in Patients with Mild Alzheimer’s Disease: A Pilot Study. Healthcare 2022, 10, 581
por: Lin, Chien-Hung, et al.
Publicado: (2022)

Peroxisome Proliferator-Activated Receptor γ Coactivator 1α Activates Vascular Endothelial Growth Factor That Protects Against Neuronal Cell Death Following Status Epilepticus through PI3K/AKT and MEK/ERK Signaling
por: Huang, Jyun-Bin, et al.
Publicado: (2020)

Zonisamide for the Treatment of Parkinson Disease: A Current Update
por: Li, Chengqian, et al.
Publicado: (2020)

Impact of Pregnancy on Zonisamide Pharmacokinetics in Rabbits
por: Matar, Kamal M.
Publicado: (2013)

Repositioning again of zonisamide for nerve regeneration
por: Ohno, Kinji, et al.
Publicado: (2016)

Zonisamide-induced acute kidney injury
por: Dixit, Deepali, et al.
Publicado: (2015)

Zonisamide-Induced Hallucinations: An Anticonvulsant’s Psychosis
por: Al Armashi, Abdul Rahman, et al.
Publicado: (2021)

Cognitive Profile of Zonisamide and Valproic Acid in the Treatment of Idiopathic Generalized Epilepsy: A Comparative Observational Study
por: Ramirez-García, Teresa, et al.
Publicado: (2016)

Nonalcoholic Fatty Liver Disease Is Related to Abnormal Corrected QT Interval and Left Ventricular Hypertrophy in Chinese Male Steelworkers
por: Hung, Wei-Chin, et al.
Publicado: (2022)

Metabolic causes and consequences of nonalcoholic fatty liver disease (NAFLD)
por: Zarghamravanbakhsh, Paria, et al.
Publicado: (2021)

Neuromuscular abnormality and autonomic dysfunction in patients with cerebrotendinous xanthomatosis
por: Chen, Shu-Fang, et al.
Publicado: (2011)

Circulating fatty acid-binding protein 1 (FABP1) and nonalcoholic fatty liver disease in patients with type 2 diabetes mellitus
por: Lu, Yung-Chuan, et al.
Publicado: (2020)

Serum Levels of Soluble Triggering Receptor Expressed on Myeloid Cells-1 Associated with the Severity and Outcome of Acute Ischemic Stroke
por: Huang, Jyun-Bin, et al.
Publicado: (2020)

Role of Fatty Liver Index and Metabolic Factors in the Prediction of Nonalcoholic Fatty Liver Disease in a Lean Population Receiving Health Checkup
por: Hsu, Chiao-Lin, et al.
Publicado: (2019)

Zonisamide is effective in the preventive therapy of chronic migraine
por: Belvis, R, et al.
Publicado: (2013)

Probable drug-induced lupus erythematosus by zonisamide
por: Safadi, Mohannad G., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_krn1j7slgb5cvo329hmt9qm7vt