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Computational and Mass Spectrometry-Based Approach Identify Deleterious Non-Synonymous Single Nucleotide Polymorphisms (nsSNPs) in JMJD6

The jumonji domain-containing protein 6 (JMJD6) gene catalyzes the arginine demethylation and lysine hydroxylation of histone and a growing list of its known substrate molecules, including p53 and U2AF65, suggesting a possible role in mRNA splicing and transcription in cancer progression. Mass spect...

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Detalles Bibliográficos
Autores principales:	Gong, Tianqi, Yang, Lujie, Shen, Fenglin, Chen, Hao, Pan, Ziyue, Zhang, Quanqing, Jiang, Yan, Zhong, Fan, Yang, Pengyuan, Zhang, Yang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347302/ https://www.ncbi.nlm.nih.gov/pubmed/34361805 http://dx.doi.org/10.3390/molecules26154653

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