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Return-to-Work Screening by Linear Discriminant Analysis of Heart Rate Variability Indices in Depressed Subjects
Using a linear discriminant analysis of heart rate variability (HRV) indices, the present study sought to verify the usefulness of autonomic measurement in major depressive disorder (MDD) patients by assessing the feasibility of their return to work after sick leave. When reinstatement was scheduled...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347333/ https://www.ncbi.nlm.nih.gov/pubmed/34372412 http://dx.doi.org/10.3390/s21155177 |
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author | Shinba, Toshikazu Murotsu, Keizo Usui, Yosuke Andow, Yoshinori Terada, Hiroshi Kariya, Nobutoshi Tatebayashi, Yoshitaka Matsuda, Yoshiki Mugishima, Go Shinba, Yujiro Sun, Guanghao Matsui, Takemi |
author_facet | Shinba, Toshikazu Murotsu, Keizo Usui, Yosuke Andow, Yoshinori Terada, Hiroshi Kariya, Nobutoshi Tatebayashi, Yoshitaka Matsuda, Yoshiki Mugishima, Go Shinba, Yujiro Sun, Guanghao Matsui, Takemi |
author_sort | Shinba, Toshikazu |
collection | PubMed |
description | Using a linear discriminant analysis of heart rate variability (HRV) indices, the present study sought to verify the usefulness of autonomic measurement in major depressive disorder (MDD) patients by assessing the feasibility of their return to work after sick leave. When reinstatement was scheduled, patients’ HRV was measured using a wearable electrocardiogram device. The outcome of the reinstatement was evaluated at one month after returning to work. HRV indices including high- and low-frequency components were calculated in three conditions within a session: initial rest, mental task, and rest after task. A linear discriminant function was made using the HRV indices of 30 MDD patients from our previous study to effectively discriminate the successful reinstatement from the unsuccessful reinstatement; this was then tested on 52 patients who participated in the present study. The discriminant function showed that the sensitivity and specificity in discriminating successful from unsuccessful returns were 95.8% and 35.7%, respectively. Sensitivity is high, indicating that normal HRV is required for a successful return, and that the discriminant analysis of HRV indices is useful for return-to-work screening in MDD patients. On the other hand, specificity is low, suggesting that other factors may also affect the outcome of reinstatement. |
format | Online Article Text |
id | pubmed-8347333 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-83473332021-08-08 Return-to-Work Screening by Linear Discriminant Analysis of Heart Rate Variability Indices in Depressed Subjects Shinba, Toshikazu Murotsu, Keizo Usui, Yosuke Andow, Yoshinori Terada, Hiroshi Kariya, Nobutoshi Tatebayashi, Yoshitaka Matsuda, Yoshiki Mugishima, Go Shinba, Yujiro Sun, Guanghao Matsui, Takemi Sensors (Basel) Article Using a linear discriminant analysis of heart rate variability (HRV) indices, the present study sought to verify the usefulness of autonomic measurement in major depressive disorder (MDD) patients by assessing the feasibility of their return to work after sick leave. When reinstatement was scheduled, patients’ HRV was measured using a wearable electrocardiogram device. The outcome of the reinstatement was evaluated at one month after returning to work. HRV indices including high- and low-frequency components were calculated in three conditions within a session: initial rest, mental task, and rest after task. A linear discriminant function was made using the HRV indices of 30 MDD patients from our previous study to effectively discriminate the successful reinstatement from the unsuccessful reinstatement; this was then tested on 52 patients who participated in the present study. The discriminant function showed that the sensitivity and specificity in discriminating successful from unsuccessful returns were 95.8% and 35.7%, respectively. Sensitivity is high, indicating that normal HRV is required for a successful return, and that the discriminant analysis of HRV indices is useful for return-to-work screening in MDD patients. On the other hand, specificity is low, suggesting that other factors may also affect the outcome of reinstatement. MDPI 2021-07-30 /pmc/articles/PMC8347333/ /pubmed/34372412 http://dx.doi.org/10.3390/s21155177 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Shinba, Toshikazu Murotsu, Keizo Usui, Yosuke Andow, Yoshinori Terada, Hiroshi Kariya, Nobutoshi Tatebayashi, Yoshitaka Matsuda, Yoshiki Mugishima, Go Shinba, Yujiro Sun, Guanghao Matsui, Takemi Return-to-Work Screening by Linear Discriminant Analysis of Heart Rate Variability Indices in Depressed Subjects |
title | Return-to-Work Screening by Linear Discriminant Analysis of Heart Rate Variability Indices in Depressed Subjects |
title_full | Return-to-Work Screening by Linear Discriminant Analysis of Heart Rate Variability Indices in Depressed Subjects |
title_fullStr | Return-to-Work Screening by Linear Discriminant Analysis of Heart Rate Variability Indices in Depressed Subjects |
title_full_unstemmed | Return-to-Work Screening by Linear Discriminant Analysis of Heart Rate Variability Indices in Depressed Subjects |
title_short | Return-to-Work Screening by Linear Discriminant Analysis of Heart Rate Variability Indices in Depressed Subjects |
title_sort | return-to-work screening by linear discriminant analysis of heart rate variability indices in depressed subjects |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347333/ https://www.ncbi.nlm.nih.gov/pubmed/34372412 http://dx.doi.org/10.3390/s21155177 |
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