Cargando…

The Essential Role of PRAK in Preserving Cardiac Function and Insulin Resistance in High-Fat Diet-Induced Diabetes

Regulated/activated protein kinase (PRAK) plays a crucial role in modulating biological function. However, the role of PRAK in mediating cardiac dysfunction and metabolic disorders remains unclear. We examined the effects of deletion of PRAK on modulating cardiac function and insulin resistance in m...

Descripción completa

Detalles Bibliográficos
Autores principales:	Du, Jianfeng, Zhao, Yu Tina, Wang, Hao, Zhang, Ling X., Qin, Gangjian, Zhuang, Shougang, Kadin, Marshall, Chin, Y. Eugene, Liu, Paul Y., Zhao, Ting C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347374/ https://www.ncbi.nlm.nih.gov/pubmed/34360761 http://dx.doi.org/10.3390/ijms22157995

Ejemplares similares

Deletion of PRAK Mitigates the Mitochondria Function and Suppresses Insulin Signaling in C2C12 Myoblasts Exposed to High Glucose
por: Zhang, Ling, et al.
Publicado: (2021)

Irisin Preserves Cardiac Performance and Insulin Sensitivity in Response to Hemorrhage
por: Kulthinee, Supaporn, et al.
Publicado: (2022)

The essential role of PRAK in tumor metastasis and its therapeutic potential
por: Wang, Yuqing, et al.
Publicado: (2021)

Irisin Improves Myocardial Performance and Attenuates Insulin Resistance in Spontaneous Mutation (Lepr(db)) Mice
por: Wang, Jianguo, et al.
Publicado: (2020)

PRAK Is Required for the Formation of Neutrophil Extracellular Traps
por: Wang, Yan, et al.
Publicado: (2019)

Histone deacetylase (HDAC) inhibition improves myocardial function and prevents cardiac remodeling in diabetic mice
por: Chen, Youfang, et al.
Publicado: (2015)

Inhibition of Oct 3/4 mitigates the cardiac progenitor-derived myocardial repair in infarcted myocardium
por: Zhao, Yu Tina, et al.
Publicado: (2015)

Inactivation of Rheb by PRAK-mediated phosphorylation is essential for energy depletion-induced suppression of mTORC1
por: Zheng, Min, et al.
Publicado: (2011)

PRAK mediates Aβ-RAGE driven autophagy pathway
por: Kim, Yoonhee, et al.
Publicado: (2017)

PRAK Interacts with DJ-1 and Prevents Oxidative Stress-Induced Cell Death
por: Tang, Jing, et al.
Publicado: (2014)

The novel RAGE interactor PRAK is associated with autophagy signaling in Alzheimer’s disease pathogenesis
por: Kim, Yoonhee, et al.
Publicado: (2016)

PRAK Promotes the Pathogen Clearance by Macrophage Through Regulating Autophagy and Inflammasome Activation
por: Mi, Ligu, et al.
Publicado: (2021)

The PRAK-NRF2 axis promotes the differentiation of Th17 cells by mediating the redox homeostasis and glycolysis
por: Zhao, Ziheng, et al.
Publicado: (2023)

Myocyte-specific overexpressing HDAC4 promotes myocardial ischemia/reperfusion injury
por: Zhang, Ling, et al.
Publicado: (2018)

The diterpenoid alkaloid noroxoaconitine is a Mapkap kinase 5 (MK5/PRAK) inhibitor
por: Kostenko, Sergiy, et al.
Publicado: (2010)

Effect of high fat diet on insulin resistance: dietary fat versus visceral fat mass.
por: Park, S., et al.
Publicado: (2001)

Comparative Analysis of Two Gene-Targeting Approaches Challenges the Tumor-Suppressive Role of the Protein Kinase MK5/PRAK
por: Ronkina, Natalia, et al.
Publicado: (2015)

PRAK-03202: A triple antigen virus-like particle vaccine candidate against SARS CoV-2
por: Mazumder, Saumyabrata, et al.
Publicado: (2021)

Irisin Ameliorates Hypoxia/Reoxygenation-Induced Injury through Modulation of Histone Deacetylase 4
por: Zhao, Yu Tina, et al.
Publicado: (2016)

Rottlerin-Mediated Inhibition of Chlamydia trachomatis Growth and Uptake of Sphingolipids Is Independent of p38-Regulated/Activated Protein Kinase (PRAK)
por: Lei, Lei, et al.
Publicado: (2012)

Cadmium and High-Fat Diet Disrupt Renal, Cardiac and Hepatic Essential Metals
por: Young, Jamie L., et al.
Publicado: (2019)

PTPRT Regulates High-Fat Diet-Induced Obesity and Insulin Resistance
por: Feng, Xiujing, et al.
Publicado: (2014)

High-Fat Diet Induces Hepatic Insulin Resistance and Impairment of Synaptic Plasticity
por: Liu, Zhigang, et al.
Publicado: (2015)

Views on high-fat diet linked insulin resistance
por: Daniel, Priscilla, et al.
Publicado: (2022)

Insulin access to skeletal muscle is preserved in obesity induced by polyunsaturated diet
por: Broussard, Josiane L., et al.
Publicado: (2017)

Neutrophils mediate insulin resistance in high fat diet fed mice via secreted elastase
por: Talukdar, Saswata, et al.
Publicado: (2012)

Impact of Cyanidin-3-Glucoside on Gut Microbiota and Relationship with Metabolism and Inflammation in High Fat-High Sucrose Diet-Induced Insulin Resistant Mice
por: Huang, Fei, et al.
Publicado: (2020)

AMPK and Insulin Action - Responses to Ageing and High Fat Diet
por: Frøsig, Christian, et al.
Publicado: (2013)

Changes of insulin receptors in high fat and high glucose diet mice with insulin resistance
por: Lei, Chen, et al.
Publicado: (2023)

Publisher Correction: Cadmium and High-Fat Diet Disrupt Renal, Cardiac and Hepatic Essential Metals
por: Young, Jamie L., et al.
Publicado: (2020)

Osteocalcin prevents insulin resistance, hepatic inflammation, and activates autophagy associated with high-fat diet–induced fatty liver hemorrhagic syndrome in aged laying hens
por: Wu, X.L., et al.
Publicado: (2020)

Effects of lobeglitazone on insulin resistance and hepatic steatosis in high-fat diet-fed mice
por: Choi, Bong-Hoi, et al.
Publicado: (2018)

Dose-Responses Relationship in Glucose Lowering and Gut Dysbiosis to Saskatoon Berry Powder Supplementation in High Fat-High Sucrose Diet-Induced Insulin Resistant Mice
por: Zhao, Ruozhi, et al.
Publicado: (2021)

Oat beta-glucan ameliorates insulin resistance in mice fed on high-fat and high-fructose diet
por: Zheng, Jie, et al.
Publicado: (2013)

Disruption of essential metal homeostasis in the brain by cadmium and high-fat diet
por: Mazzocco, John C., et al.
Publicado: (2020)

Ectopic Fat and Insulin Resistance: Pathophysiology and Effect of Diet and Lifestyle Interventions
por: Snel, M., et al.
Publicado: (2012)

Hedgehog Interacting Protein (Hhip) Regulates Insulin Secretion in Mice Fed High Fat Diets
por: Nchienzia, Henry, et al.
Publicado: (2019)

Corrigendum to “PRAK-03202: A triple antigen virus-like particle vaccine candidate against SARS CoV-2”[Heliyon 7 (10) (October 2021) e08124]
por: Mazumder, Saumyabrata, et al.
Publicado: (2021)

Inhibition of Serine Protease Activity Protects Against High Fat Diet-Induced Inflammation and Insulin Resistance
por: Kuo, Chin-Sung, et al.
Publicado: (2020)

Severe Maternal Hyperglycemia Exacerbates the Development of Insulin Resistance and Fatty Liver in the Offspring on High Fat Diet
por: Song, Yong, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_9edelbq0mo1t7cm0vtvqcrohnh