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Benzo[a]pyrene-Induced Genotoxicity in Rats Is Affected by Co-Exposure to Sudan I by Altering the Expression of Biotransformation Enzymes

The environmental pollutant benzo[a]pyrene (BaP) is a human carcinogen that reacts with DNA after metabolic activation catalysed by cytochromes P450 (CYP) 1A1 and 1B1 together with microsomal epoxide hydrolase. The azo dye Sudan I is a potent inducer of CYP1A1/2. Here, Wistar rats were either treate...

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Detalles Bibliográficos
Autores principales:	Dračínská, Helena, Indra, Radek, Jelínková, Sandra, Černá, Věra, Arlt, Volker Manfred, Stiborová, Marie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347376/ https://www.ncbi.nlm.nih.gov/pubmed/34360828 http://dx.doi.org/10.3390/ijms22158062

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