Recent Advances in the Excipients Used for Modified Ocular Drug Delivery

In ocular drug delivery, maintaining an efficient concentration of the drug in the target area for a sufficient period of time is a challenging task. There is a pressing need for the development of effective strategies for drug delivery to the eye using recent advances in material sciences and novel...

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Autores principales: Koutsoviti, Melitini, Siamidi, Angeliki, Pavlou, Panagoula, Vlachou, Marilena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347600/
https://www.ncbi.nlm.nih.gov/pubmed/34361483
http://dx.doi.org/10.3390/ma14154290
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author Koutsoviti, Melitini
Siamidi, Angeliki
Pavlou, Panagoula
Vlachou, Marilena
author_facet Koutsoviti, Melitini
Siamidi, Angeliki
Pavlou, Panagoula
Vlachou, Marilena
author_sort Koutsoviti, Melitini
collection PubMed
description In ocular drug delivery, maintaining an efficient concentration of the drug in the target area for a sufficient period of time is a challenging task. There is a pressing need for the development of effective strategies for drug delivery to the eye using recent advances in material sciences and novel approaches to drug delivery. This review summarizes the important aspects of ocular drug delivery and the factors affecting drug absorption in the eye including encapsulating excipients (chitosan, hyaluronic acid, poloxamer, PLGA, PVCL-PVA-PEG, cetalkonium chloride, and gelatin) for modified drug delivery.
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spelling pubmed-83476002021-08-08 Recent Advances in the Excipients Used for Modified Ocular Drug Delivery Koutsoviti, Melitini Siamidi, Angeliki Pavlou, Panagoula Vlachou, Marilena Materials (Basel) Review In ocular drug delivery, maintaining an efficient concentration of the drug in the target area for a sufficient period of time is a challenging task. There is a pressing need for the development of effective strategies for drug delivery to the eye using recent advances in material sciences and novel approaches to drug delivery. This review summarizes the important aspects of ocular drug delivery and the factors affecting drug absorption in the eye including encapsulating excipients (chitosan, hyaluronic acid, poloxamer, PLGA, PVCL-PVA-PEG, cetalkonium chloride, and gelatin) for modified drug delivery. MDPI 2021-07-31 /pmc/articles/PMC8347600/ /pubmed/34361483 http://dx.doi.org/10.3390/ma14154290 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Koutsoviti, Melitini
Siamidi, Angeliki
Pavlou, Panagoula
Vlachou, Marilena
Recent Advances in the Excipients Used for Modified Ocular Drug Delivery
title Recent Advances in the Excipients Used for Modified Ocular Drug Delivery
title_full Recent Advances in the Excipients Used for Modified Ocular Drug Delivery
title_fullStr Recent Advances in the Excipients Used for Modified Ocular Drug Delivery
title_full_unstemmed Recent Advances in the Excipients Used for Modified Ocular Drug Delivery
title_short Recent Advances in the Excipients Used for Modified Ocular Drug Delivery
title_sort recent advances in the excipients used for modified ocular drug delivery
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347600/
https://www.ncbi.nlm.nih.gov/pubmed/34361483
http://dx.doi.org/10.3390/ma14154290
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