The Influence of pH on Complexation Process of Copper(II) Phosphoethanolamine to Pyrimidine Nucleosides

The influence of pH on the complex formation of phosphoethanolamine and pyrimidine nucleosides (uridine, cytidine and thymidine) with copper(II) ions was studied. All investigations were performed in aqueous solution. The overall stability constants of the complexes and non-covalent compounds were o...

Descripción completa

Detalles Bibliográficos
Autores principales: Gabryel-Skrodzka, Malwina, Nowak, Martyna, Stachowiak, Klaudia, Zabiszak, Michal, Ogawa, Kazuma, Jastrzab, Renata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347602/
https://www.ncbi.nlm.nih.gov/pubmed/34361504
http://dx.doi.org/10.3390/ma14154309
_version_ 1783735130507968512
author Gabryel-Skrodzka, Malwina
Nowak, Martyna
Stachowiak, Klaudia
Zabiszak, Michal
Ogawa, Kazuma
Jastrzab, Renata
author_facet Gabryel-Skrodzka, Malwina
Nowak, Martyna
Stachowiak, Klaudia
Zabiszak, Michal
Ogawa, Kazuma
Jastrzab, Renata
author_sort Gabryel-Skrodzka, Malwina
collection PubMed
description The influence of pH on the complex formation of phosphoethanolamine and pyrimidine nucleosides (uridine, cytidine and thymidine) with copper(II) ions was studied. All investigations were performed in aqueous solution. The overall stability constants of the complexes and non-covalent compounds were obtained using the potentiometric method with computer calculation of the data. Moreover, equilibrium constants of the reaction were determined. The mode of coordination was obtained using spectroscopic methods. Analysis of the potentiometric and spectroscopic data confirmed the involvement and effectiveness of phosphate groups in species formation as well as the influence of pH on the mode of coordination of the investigated biomaterials. In the next step, studied complexes will be applied as potential biomaterials with biological applications.
format Online
Article
Text
id pubmed-8347602
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-83476022021-08-08 The Influence of pH on Complexation Process of Copper(II) Phosphoethanolamine to Pyrimidine Nucleosides Gabryel-Skrodzka, Malwina Nowak, Martyna Stachowiak, Klaudia Zabiszak, Michal Ogawa, Kazuma Jastrzab, Renata Materials (Basel) Article The influence of pH on the complex formation of phosphoethanolamine and pyrimidine nucleosides (uridine, cytidine and thymidine) with copper(II) ions was studied. All investigations were performed in aqueous solution. The overall stability constants of the complexes and non-covalent compounds were obtained using the potentiometric method with computer calculation of the data. Moreover, equilibrium constants of the reaction were determined. The mode of coordination was obtained using spectroscopic methods. Analysis of the potentiometric and spectroscopic data confirmed the involvement and effectiveness of phosphate groups in species formation as well as the influence of pH on the mode of coordination of the investigated biomaterials. In the next step, studied complexes will be applied as potential biomaterials with biological applications. MDPI 2021-08-01 /pmc/articles/PMC8347602/ /pubmed/34361504 http://dx.doi.org/10.3390/ma14154309 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Gabryel-Skrodzka, Malwina
Nowak, Martyna
Stachowiak, Klaudia
Zabiszak, Michal
Ogawa, Kazuma
Jastrzab, Renata
The Influence of pH on Complexation Process of Copper(II) Phosphoethanolamine to Pyrimidine Nucleosides
title The Influence of pH on Complexation Process of Copper(II) Phosphoethanolamine to Pyrimidine Nucleosides
title_full The Influence of pH on Complexation Process of Copper(II) Phosphoethanolamine to Pyrimidine Nucleosides
title_fullStr The Influence of pH on Complexation Process of Copper(II) Phosphoethanolamine to Pyrimidine Nucleosides
title_full_unstemmed The Influence of pH on Complexation Process of Copper(II) Phosphoethanolamine to Pyrimidine Nucleosides
title_short The Influence of pH on Complexation Process of Copper(II) Phosphoethanolamine to Pyrimidine Nucleosides
title_sort influence of ph on complexation process of copper(ii) phosphoethanolamine to pyrimidine nucleosides
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347602/
https://www.ncbi.nlm.nih.gov/pubmed/34361504
http://dx.doi.org/10.3390/ma14154309
work_keys_str_mv AT gabryelskrodzkamalwina theinfluenceofphoncomplexationprocessofcopperiiphosphoethanolaminetopyrimidinenucleosides
AT nowakmartyna theinfluenceofphoncomplexationprocessofcopperiiphosphoethanolaminetopyrimidinenucleosides
AT stachowiakklaudia theinfluenceofphoncomplexationprocessofcopperiiphosphoethanolaminetopyrimidinenucleosides
AT zabiszakmichal theinfluenceofphoncomplexationprocessofcopperiiphosphoethanolaminetopyrimidinenucleosides
AT ogawakazuma theinfluenceofphoncomplexationprocessofcopperiiphosphoethanolaminetopyrimidinenucleosides
AT jastrzabrenata theinfluenceofphoncomplexationprocessofcopperiiphosphoethanolaminetopyrimidinenucleosides
AT gabryelskrodzkamalwina influenceofphoncomplexationprocessofcopperiiphosphoethanolaminetopyrimidinenucleosides
AT nowakmartyna influenceofphoncomplexationprocessofcopperiiphosphoethanolaminetopyrimidinenucleosides
AT stachowiakklaudia influenceofphoncomplexationprocessofcopperiiphosphoethanolaminetopyrimidinenucleosides
AT zabiszakmichal influenceofphoncomplexationprocessofcopperiiphosphoethanolaminetopyrimidinenucleosides
AT ogawakazuma influenceofphoncomplexationprocessofcopperiiphosphoethanolaminetopyrimidinenucleosides
AT jastrzabrenata influenceofphoncomplexationprocessofcopperiiphosphoethanolaminetopyrimidinenucleosides

Ejemplares similares