Progressive Mitochondrial SOD1(G93A) Accumulation Causes Severe Structural, Metabolic and Functional Aberrations through OPA1 Down-Regulation in a Mouse Model of Amyotrophic Lateral Sclerosis

In recent years, the “non-autonomous motor neuron death” hypothesis has become more consolidated behind amyotrophic lateral sclerosis (ALS). It postulates that cells other than motor neurons participate in the pathology. In fact, the involvement of the autonomic nervous system is fundamental since p...

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Detalles Bibliográficos
Autores principales: Méndez-López, Iago, Sancho-Bielsa, Francisco J., Engel, Tobias, García, Antonio G., Padín, Juan Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347639/
https://www.ncbi.nlm.nih.gov/pubmed/34360957
http://dx.doi.org/10.3390/ijms22158194

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