Cargando…

A Novel NIR Fluorescent Probe for Highly Selective Detection of Nitroreductase and Hypoxic-Tumor-Cell Imaging

Nitroreductase as a potential biomarker for aggressive tumors has received extensive attention. In this work, a novel NIR fluorescent probe for nitroreductase detection was synthesized. The probe Py-SiRh-NTR displayed excellent sensitivity and selectivity. Most importantly, the confocal fluorescence...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Feng, Zhang, Hong, Li, Kun, Xie, Yongmei, Li, Zhihui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347683/ https://www.ncbi.nlm.nih.gov/pubmed/34361578 http://dx.doi.org/10.3390/molecules26154425

Ejemplares similares

Hypoxia imaging in cells and tumor tissues using a highly selective fluorescent nitroreductase probe
por: Yang, Dan, et al.
Publicado: (2017)

A nitroreductase responsive and photoactivated fluorescent probe for dual-controlled tumor hypoxia imaging
por: Xu, Jialong, et al.
Publicado: (2022)

An Activatable Lanthanide Luminescent Probe for Time‐Gated Detection of Nitroreductase in Live Bacteria
por: Brennecke, Benjamin, et al.
Publicado: (2020)

A fast-responsive fluorescent turn-on probe for nitroreductase imaging in living cells
por: Jia, Chengli, et al.
Publicado: (2021)

Development of a Bioluminescent Nitroreductase Probe for Preclinical Imaging
por: Vorobyeva, Anzhelika G., et al.
Publicado: (2015)

Hemicyanine-Based Near-Infrared Fluorescence Off–On Probes for Imaging Intracellular and In Vivo Nitroreductase Activity
por: Lee, Sun Hyeok, et al.
Publicado: (2023)

Asymmetric and Reduced Xanthene Fluorophores: Synthesis, Photochemical Properties, and Application to Activatable Fluorescent Probes for Detection of Nitroreductase
por: More, Kunal N., et al.
Publicado: (2019)

Design and Synthesis of a Novel NIR Celecoxib-Based Fluorescent Probe for Cyclooxygenase-2 Targeted Bioimaging in Tumor Cells
por: Wang, Xinli, et al.
Publicado: (2020)

A NIR fluorescent smart probe for imaging tumor hypoxia
por: Hettie, Kenneth S., et al.
Publicado: (2021)

Hypoxia-activated probe for NIR fluorescence and photoacoustic dual-mode tumor imaging
por: Li, Meng, et al.
Publicado: (2021)

A Novel Fluorescent Probe for Selective Detection of Hydrazine and Its Application in Imaging
por: Man, Ruo-Jun, et al.
Publicado: (2021)

Ratiometric Fluorescence Assay for Nitroreductase Activity: Locked-Flavylium Fluorophore as a NTR-Sensitive Molecular Probe
por: Kim, Su Jung, et al.
Publicado: (2021)

APPLICATION OF 6-NITROCOUMARIN AS A SUBSTRATE FOR THE FLUORESCENT DETECTION OF NITROREDUCTASE ACTIVITY IN Sporothrix schenckii
por: Stopiglia, Cheila Denise Ottonelli, et al.
Publicado: (2013)

Novel NIR-II fluorescent probes for biliary atresia imaging
por: Zeng, Xiaodong, et al.
Publicado: (2023)

A novel NIR-II probe for improved tumor-targeting NIR-II imaging
por: Hu, Chao, et al.
Publicado: (2021)

A novel nitroreductase-enhanced MRI contrast agent and its potential application in bacterial imaging
por: Liu, Yun, et al.
Publicado: (2018)

Human-T-Cell-Selective Fluorescent Probe
por: Gao, Min, et al.
Publicado: (2022)

Activatable NIR-II organic fluorescent probes for bioimaging
por: Zhang, Xiaoning, et al.
Publicado: (2022)

Recent Progress on NIR Fluorescent Probes for Enzymes
por: Zhao, Jintao, et al.
Publicado: (2022)

Fe‐Doped Carbon Dots as NIR‐II Fluorescence Probe for In Vivo Gastric Imaging and pH Detection
por: Ci, Qiaoqiao, et al.
Publicado: (2023)

Centimeter-Deep NIR-II Fluorescence Imaging with Nontoxic AIE Probes in Nonhuman Primates
por: Sheng, Zonghai, et al.
Publicado: (2020)

Lighting-Up Tumor for Assisting Resection via Spraying NIR Fluorescent Probe of γ-Glutamyltranspeptidas
por: Li, Haidong, et al.
Publicado: (2018)

Evolutionary aspects of the Viridiplantae nitroreductases
por: Dabravolski, Siarhei A.
Publicado: (2020)

The Role of Nitroreductases in Resistance to Nitroimidazoles
por: Thomas, Carol, et al.
Publicado: (2021)

Nitroreductase Activites in Giardia lamblia: ORF 17150 Encodes a Quinone Reductase with Nitroreductase Activity
por: Müller, Joachim, et al.
Publicado: (2021)

A Highly Selective NIR Fluorescent Turn-on Probe for Hydroxyl Radical and Its Application in Living Cell Images
por: Qu, Xingyu, et al.
Publicado: (2019)

A Selective Fluorescence Turn-On Probe for the Detection of DCNP (Nerve Agent Tabun Simulant)
por: Jung, Yuna, et al.
Publicado: (2019)

Identification of a type I nitroreductase gene in non-virulent Trypanosoma rangeli
por: Montenegro, Marjorie, et al.
Publicado: (2017)

A NIR fluorescent probe for Vanin-1 and its applications in imaging, kidney injury diagnosis, and the development of inhibitor
por: Tian, Zhenhao, et al.
Publicado: (2022)

A molecular design towards sulfonyl aza-BODIPY based NIR fluorescent and colorimetric probe for selective cysteine detection
por: Pham, Thanh Chung, et al.
Publicado: (2021)

A novel CXCR4-targeted near-infrared (NIR) fluorescent probe (Peptide R-NIR750) specifically detects CXCR4 expressing tumors
por: Santagata, Sara, et al.
Publicado: (2017)

Stimuli-responsive colorimetric and NIR fluorescence combination probe for selective reporting of cellular hydrogen peroxide
por: Narayanaswamy, Nagarjun, et al.
Publicado: (2016)

Boronate‐Based Fluorescence Probes for the Detection of Hydrogen Peroxide
por: Lampard, Emma V., et al.
Publicado: (2018)

A Novel Fluorescent Probe for the Detection of Hydrogen Peroxide
por: Wang, Kangkang, et al.
Publicado: (2023)

2D Strategy for the Construction of an Enzyme-Activated NIR Fluorophore Suitable for the Visual Sensing and Profiling of Homologous Nitroreductases from Various Bacterial Species
por: Liu, Tao, et al.
Publicado: (2021)

The Development of Novel Near-Infrared (NIR) Tetraarylazadipyrromethene Fluorescent Dyes
por: Lee, Sung-Chan, et al.
Publicado: (2013)

A highly sensitive and selective fluorescent probe without quencher for detection of Pb(2+) ions based on aggregation-caused quenching phenomenon
por: Li, Qianyun, et al.
Publicado: (2018)

Improved Tumor Targeting and Longer Retention Time of NIR Fluorescent Probes Using Bioorthogonal Chemistry
por: Zhang, Xianghan, et al.
Publicado: (2017)

A New Fluorescent Probe for Hydrogen Sulfide Detection in Solution and Living Cells
por: Feng, Wei, et al.
Publicado: (2023)

A pyrene-based ratiometric fluorescent probe with a large Stokes shift for selective detection of hydrogen peroxide in living cells
por: Chen, Qingxin, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_5kfcsnvrvb3ltmbpoab99poj0o