Anti-Idiotype scFv Localizes an Autoepitope in the Globular Domain of C1q

We addressed the issue of C1q autoantigenicity by studying the structural features of the autoepitopes recognized by the polyclonal anti-C1q antibodies present in Lupus Nephritis (LN) sera. We used six fractions of anti-C1q as antigens and selected anti-idiotypic scFv antibodies from the phage libra...

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Detalles Bibliográficos
Autores principales: Todorova, Nadezhda, Rangelov, Miroslav, Bogoeva, Vanya, Stoyanova, Vishnya, Yordanova, Anna, Nikolova, Ginka, Georgiev, Hristo, Dimitrova, Daniela, Mohedin, Safa, Stoyanova, Katerina, Tsacheva, Ivanka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347764/
https://www.ncbi.nlm.nih.gov/pubmed/34361054
http://dx.doi.org/10.3390/ijms22158288

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347764/
https://www.ncbi.nlm.nih.gov/pubmed/34361054
http://dx.doi.org/10.3390/ijms22158288

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