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Anti-Idiotype scFv Localizes an Autoepitope in the Globular Domain of C1q
We addressed the issue of C1q autoantigenicity by studying the structural features of the autoepitopes recognized by the polyclonal anti-C1q antibodies present in Lupus Nephritis (LN) sera. We used six fractions of anti-C1q as antigens and selected anti-idiotypic scFv antibodies from the phage libra...
Autores principales: | Todorova, Nadezhda, Rangelov, Miroslav, Bogoeva, Vanya, Stoyanova, Vishnya, Yordanova, Anna, Nikolova, Ginka, Georgiev, Hristo, Dimitrova, Daniela, Mohedin, Safa, Stoyanova, Katerina, Tsacheva, Ivanka |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347764/ https://www.ncbi.nlm.nih.gov/pubmed/34361054 http://dx.doi.org/10.3390/ijms22158288 |
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