Ncx3-Induced Mitochondrial Dysfunction in Midbrain Leads to Neuroinflammation in Striatum of A53t-α-Synuclein Transgenic Old Mice

The exact mechanism underlying selective dopaminergic neurodegeneration is not completely understood. The complex interplay among toxic alpha-synuclein aggregates, oxidative stress, altered intracellular Ca(2+)-homeostasis, mitochondrial dysfunction and disruption of mitochondrial integrity is consi...

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Detalles Bibliográficos
Autores principales: Di Martino, Rossana, Sisalli, Maria Josè, Sirabella, Rossana, Della Notte, Salvatore, Borzacchiello, Domenica, Feliciello, Antonio, Annunziato, Lucio, Scorziello, Antonella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347885/
https://www.ncbi.nlm.nih.gov/pubmed/34360942
http://dx.doi.org/10.3390/ijms22158177

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347885/
https://www.ncbi.nlm.nih.gov/pubmed/34360942
http://dx.doi.org/10.3390/ijms22158177

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