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Ncx3-Induced Mitochondrial Dysfunction in Midbrain Leads to Neuroinflammation in Striatum of A53t-α-Synuclein Transgenic Old Mice
The exact mechanism underlying selective dopaminergic neurodegeneration is not completely understood. The complex interplay among toxic alpha-synuclein aggregates, oxidative stress, altered intracellular Ca(2+)-homeostasis, mitochondrial dysfunction and disruption of mitochondrial integrity is consi...
Autores principales: | Di Martino, Rossana, Sisalli, Maria Josè, Sirabella, Rossana, Della Notte, Salvatore, Borzacchiello, Domenica, Feliciello, Antonio, Annunziato, Lucio, Scorziello, Antonella |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347885/ https://www.ncbi.nlm.nih.gov/pubmed/34360942 http://dx.doi.org/10.3390/ijms22158177 |
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