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Biopharmaceutical Study on Nobiletin-Loaded Amorphous Solid Dispersion with Improved Hypouricemic Effect

The present study aimed to develop an amorphous solid dispersion of nobiletin (ASD/NOB) using hydroxypropyl cellulose-SSL (HPC-SSL) to improve the pharmacokinetic properties and hypouricemic effect of NOB. ASD/NOB was prepared by the freeze-drying method (ASD/NOB). ASD/NOB was characterized with a f...

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Detalles Bibliográficos
Autores principales: Nihei, Takuya, Ushiro, Eri, Sato, Hideyuki, Onoue, Satomi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347906/
https://www.ncbi.nlm.nih.gov/pubmed/34361599
http://dx.doi.org/10.3390/molecules26154447

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