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Features of Lipid Metabolism in Humanized ApoE Knockin Rat Models
Apolipoprotein E (ApoE), an essential plasma apolipoprotein, has three isoforms (E2, E3, and E4) in humans. E2 is associated with type III hyperlipoproteinemia. E4 is the major susceptibility gene to Alzheimer’s disease (AD) and coronary heart disease (CHD). We investigated lipid metabolism and athe...
Autores principales: | Wu, Yang, Johnson, Gem, Zhao, Fujie, Wu, Yin, Zhao, Guojun, Brown, Andrew, You, Shaojin, Zou, Ming-Hui, Song, Ping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347964/ https://www.ncbi.nlm.nih.gov/pubmed/34361033 http://dx.doi.org/10.3390/ijms22158262 |
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