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Features of Lipid Metabolism in Humanized ApoE Knockin Rat Models

Apolipoprotein E (ApoE), an essential plasma apolipoprotein, has three isoforms (E2, E3, and E4) in humans. E2 is associated with type III hyperlipoproteinemia. E4 is the major susceptibility gene to Alzheimer’s disease (AD) and coronary heart disease (CHD). We investigated lipid metabolism and athe...

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Detalles Bibliográficos
Autores principales: Wu, Yang, Johnson, Gem, Zhao, Fujie, Wu, Yin, Zhao, Guojun, Brown, Andrew, You, Shaojin, Zou, Ming-Hui, Song, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347964/
https://www.ncbi.nlm.nih.gov/pubmed/34361033
http://dx.doi.org/10.3390/ijms22158262

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