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Mechanisms of Immunotoxicity: Stressors and Evaluators
The immune system defends the body against certain tumor cells and against foreign agents such as fungi, parasites, bacteria, and viruses. One of its main roles is to distinguish endogenous components from non-self-components. An unproperly functioning immune system is prone to primary immune defici...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348050/ https://www.ncbi.nlm.nih.gov/pubmed/34361007 http://dx.doi.org/10.3390/ijms22158242 |
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author | Bou Zerdan, Maroun Moussa, Sara Atoui, Ali Assi, Hazem I. |
author_facet | Bou Zerdan, Maroun Moussa, Sara Atoui, Ali Assi, Hazem I. |
author_sort | Bou Zerdan, Maroun |
collection | PubMed |
description | The immune system defends the body against certain tumor cells and against foreign agents such as fungi, parasites, bacteria, and viruses. One of its main roles is to distinguish endogenous components from non-self-components. An unproperly functioning immune system is prone to primary immune deficiencies caused by either primary immune deficiencies such as genetic defects or secondary immune deficiencies such as physical, chemical, and in some instances, psychological stressors. In the manuscript, we will provide a brief overview of the immune system and immunotoxicology. We will also describe the biochemical mechanisms of immunotoxicants and how to evaluate immunotoxicity. |
format | Online Article Text |
id | pubmed-8348050 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-83480502021-08-08 Mechanisms of Immunotoxicity: Stressors and Evaluators Bou Zerdan, Maroun Moussa, Sara Atoui, Ali Assi, Hazem I. Int J Mol Sci Review The immune system defends the body against certain tumor cells and against foreign agents such as fungi, parasites, bacteria, and viruses. One of its main roles is to distinguish endogenous components from non-self-components. An unproperly functioning immune system is prone to primary immune deficiencies caused by either primary immune deficiencies such as genetic defects or secondary immune deficiencies such as physical, chemical, and in some instances, psychological stressors. In the manuscript, we will provide a brief overview of the immune system and immunotoxicology. We will also describe the biochemical mechanisms of immunotoxicants and how to evaluate immunotoxicity. MDPI 2021-07-31 /pmc/articles/PMC8348050/ /pubmed/34361007 http://dx.doi.org/10.3390/ijms22158242 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Bou Zerdan, Maroun Moussa, Sara Atoui, Ali Assi, Hazem I. Mechanisms of Immunotoxicity: Stressors and Evaluators |
title | Mechanisms of Immunotoxicity: Stressors and Evaluators |
title_full | Mechanisms of Immunotoxicity: Stressors and Evaluators |
title_fullStr | Mechanisms of Immunotoxicity: Stressors and Evaluators |
title_full_unstemmed | Mechanisms of Immunotoxicity: Stressors and Evaluators |
title_short | Mechanisms of Immunotoxicity: Stressors and Evaluators |
title_sort | mechanisms of immunotoxicity: stressors and evaluators |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348050/ https://www.ncbi.nlm.nih.gov/pubmed/34361007 http://dx.doi.org/10.3390/ijms22158242 |
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