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Improving Human Induced Pluripotent Stem Cell-Derived Megakaryocyte Differentiation and Platelet Production

Several protocols exist for generating megakaryocytes (MKs) and platelets from human induced pluripotent stem cells (hiPSCs) with limited efficiency. We observed previously that mesoderm induction improved endothelial and stromal differentiation. We, therefore, hypothesized that a protocol modificat...

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Detalles Bibliográficos
Autores principales: Krisch, Linda, Brachtl, Gabriele, Hochmann, Sarah, Andrade, André Cronemberger, Oeller, Michaela, Ebner-Peking, Patricia, Schallmoser, Katharina, Strunk, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348107/
https://www.ncbi.nlm.nih.gov/pubmed/34360992
http://dx.doi.org/10.3390/ijms22158224