Cargando…

Protective Effect of Ciclopirox against Ovariectomy-Induced Bone Loss in Mice by Suppressing Osteoclast Formation and Function

Postmenopausal osteoporosis is closely associated with excessive osteoclast formation and function, resulting in the loss of bone mass. Osteoclast-targeting agents have been developed to manage this disease. We examined the effects of ciclopirox on osteoclast differentiation and bone resorption in v...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ihn, Hye Jung, Lim, Jiwon, Kim, Kiryeong, Nam, Sang-Hyeon, Lim, Soomin, Lee, Su Jeong, Bae, Jong-Sup, Kim, Tae Hoon, Kim, Jung-Eun, Baek, Moon-Chang, Bae, Yong Chul, Park, Eui Kyun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348120/ https://www.ncbi.nlm.nih.gov/pubmed/34361069 http://dx.doi.org/10.3390/ijms22158299

Ejemplares similares

Suppressive effects of (-)-tubaic acid on RANKL-induced osteoclast differentiation and bone resorption
por: Lim, Soomin, et al.
Publicado: (2023)

Fermented Oyster Extract Prevents Ovariectomy-Induced Bone Loss and Suppresses Osteoclastogenesis
por: Ihn, Hye Jung, et al.
Publicado: (2019)

Inhibitory Effect of Purpurogallin on Osteoclast Differentiation In Vitro through the Downregulation of c-Fos and NFATc1
por: Kim, Kiryeong, et al.
Publicado: (2018)

2-O-digalloyl-1,3,4,6-tetra-O-galloyl-β-D-glucose isolated from Galla Rhois suppresses osteoclast differentiation and function by inhibiting NF-κB signaling
por: Ihn, Hye Jung, et al.
Publicado: (2019)

Afatinib ameliorates osteoclast differentiation and function through downregulation of RANK signaling pathways
por: Ihn, Hye Jung, et al.
Publicado: (2017)

PF-3845, a Fatty Acid Amide Hydrolase Inhibitor, Directly Suppresses Osteoclastogenesis through ERK and NF-κB Pathways In Vitro and Alveolar Bone Loss In Vivo
por: Ihn, Hye-Jung, et al.
Publicado: (2021)

S100 Calcium-Binding Protein P Secreted from Megakaryocytes Promotes Osteoclast Maturation
por: Lee, Seung-Hoon, et al.
Publicado: (2021)

Rhus javanica Gall Extract Inhibits the Differentiation of Bone Marrow-Derived Osteoclasts and Ovariectomy-Induced Bone Loss
por: Kim, Tae-Ho, et al.
Publicado: (2016)

Inhibitory Effects of KP-A159, a Thiazolopyridine Derivative, on Osteoclast Differentiation, Function, and Inflammatory Bone Loss via Suppression of RANKL-Induced MAP Kinase Signaling Pathway
por: Ihn, Hye Jung, et al.
Publicado: (2015)

Isovaleric acid ameliorates ovariectomy‐induced osteoporosis by inhibiting osteoclast differentiation
por: Cho, Kwang Min, et al.
Publicado: (2021)

Britanin inhibits titanium wear particle‑induced osteolysis and osteoclastogenesis
por: Kim, Ju Ang, et al.
Publicado: (2023)

Inhibitory Effect of KP-A038 on Osteoclastogenesis and Inflammatory Bone Loss Is Associated With Downregulation of Blimp1
por: Ihn, Hye Jung, et al.
Publicado: (2019)

Sphingosylphosphorylcholine blocks ovariectomy‐induced bone loss by suppressing Ca(2+)/calmodulin‐mediated osteoclast differentiation
por: Lee, Ha Young, et al.
Publicado: (2020)

Diphlorethohydroxycarmalol from Ishige okamurae Suppresses Osteoclast Differentiation by Downregulating the NF-κB Signaling Pathway
por: Ihn, Hye Jung, et al.
Publicado: (2017)

Ciclopirox inhibits Hepatitis B Virus secretion by blocking capsid assembly
por: Kang, Jung-Ah, et al.
Publicado: (2019)

OCLI-023, a Novel Pyrimidine Compound, Suppresses Osteoclastogenesis In Vitro and Alveolar Bone Resorption In Vivo
por: Ihn, Hye Jung, et al.
Publicado: (2017)

1,3-Dibenzyl-5-Fluorouracil Prevents Ovariectomy-Induced Bone Loss by Suppressing Osteoclast Differentiation
por: Jeon, Hyoeun, et al.
Publicado: (2022)

Chaenomelis fructus inhibits osteoclast differentiation by suppressing NFATc1 expression and prevents ovariectomy-induced osteoporosis
por: Kim, Minsun, et al.
Publicado: (2020)

Solanum nigrum Line inhibits osteoclast differentiation and suppresses bone mineral density reduction in the ovariectomy-induced osteoporosis model
por: Kim, Jae-Hyun, et al.
Publicado: (2021)

Rutin Improves Bone Histomorphometric Values by Reduction of Osteoclastic Activity in Osteoporosis Mouse Model Induced by Bilateral Ovariectomy
por: Lee, Hye-Hwa, et al.
Publicado: (2020)

Plum-Derived Exosome-like Nanovesicles Induce Differentiation of Osteoblasts and Reduction of Osteoclast Activation
por: Park, Yu-Seong, et al.
Publicado: (2023)

Phillyrin Prevents Ovariectomy-Induced Osteolysis by Inhibiting Osteoclast Differentiation
por: Zhang, Geng, et al.
Publicado: (2022)

Treatment of eggshell with casein phosphopeptide reduces the severity of ovariectomy-induced bone loss
por: Kim, Jung-Hoon, et al.
Publicado: (2013)

Isosteviol Derivative Inhibits Osteoclast Differentiation and Ameliorates Ovariectomy-Induced Osteoporosis
por: Tzeng, Huey-En, et al.
Publicado: (2018)

Artemisia annua extract prevents ovariectomy-induced bone loss by blocking receptor activator of nuclear factor kappa-B ligand-induced differentiation of osteoclasts
por: Lee, Sun Kyoung, et al.
Publicado: (2017)

Amorolfine vs. ciclopirox – lacquers for the treatment of onychomycosis
por: Tabara, Katarzyna, et al.
Publicado: (2015)

Water Extract of Piper longum Linn Ameliorates Ovariectomy-Induced Bone Loss by Inhibiting Osteoclast Differentiation
por: Gu, Dong Ryun, et al.
Publicado: (2022)

Amaranthus mangostanus Inhibits the Differentiation of Osteoclasts and Prevents Ovariectomy-Induced Bone Loss
por: Jeong, Yeon-Hui, et al.
Publicado: (2020)

Loss of BRCA1 Spontaneously Induces the Tumorigenesis in Lacrimal Gland
por: Kim, Sun Eui, et al.
Publicado: (2018)

Synthetic Derivatives of Ciclopirox are Effective Inhibitors of Cryptococcus neoformans
por: Lin, Jeffrey, et al.
Publicado: (2021)

Soluble RANKL contributes to osteoclast formation in adult mice but not ovariectomy-induced bone loss
por: Xiong, Jinhu, et al.
Publicado: (2018)

Gut microbiota modulates osteoclast glutathione synthesis and mitochondrial biogenesis in mice subjected to ovariectomy
por: Yuan, Yin, et al.
Publicado: (2022)

Oroxin B Attenuates Ovariectomy-Induced Bone Loss by Suppressing Osteoclast Formation and Activity
por: Huang, Jun-ming, et al.
Publicado: (2021)

Combined Effect of Bilateral Ovariectomy and Anterior Cruciate Ligament Transection With Medial Meniscectomy on the Development of Osteoarthritis Model
por: Kim, Jae Lim, et al.
Publicado: (2016)

Repurposing of Ciclopirox to Overcome the Limitations of Zidovudine (Azidothymidine) against Multidrug-Resistant Gram-Negative Bacteria
por: Cho, Hyejin, et al.
Publicado: (2022)

SARS-CoV-2-Specific Antibody and T Cell Response Kinetics According to Symptom Severity
por: Kim, Ji Yeun, et al.
Publicado: (2021)

Protection against Ovariectomy-Induced Bone Loss by Tranilast
por: Phan, Tien Van, et al.
Publicado: (2014)

Platinum nanoparticles reduce ovariectomy-induced bone loss by decreasing osteoclastogenesis
por: Kim, Woon-Ki, et al.
Publicado: (2012)

N-[2-(4-Acetyl-1-Piperazinyl)Phenyl]-2-(3-Methylphenoxy)Acetamide (NAPMA) Inhibits Osteoclast Differentiation and Protects against Ovariectomy-Induced Osteoporosis
por: Lee, Jinkyung, et al.
Publicado: (2020)

The Effects of Kaempferol-Inhibited Autophagy on Osteoclast Formation
por: Kim, Chang-Ju, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_1hgkhnhk5hq01m1efh2597cp59