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Transcriptomic and Metabolic Network Analysis of Metabolic Reprogramming and IGF-1 Modulation in SCA3 Transgenic Mice

Spinocerebellar ataxia type 3 (SCA3) is a genetic neurodegenerative disease for which a cure is still needed. Growth hormone (GH) therapy has shown positive effects on the exercise behavior of mice with cerebellar atrophy, retains more Purkinje cells, and exhibits less DNA damage after GH interventi...

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Detalles Bibliográficos
Autores principales: Lin, Yu-Te, Lin, Yong-Shiou, Cheng, Wen-Ling, Chang, Jui-Chih, Chao, Yi-Chun, Liu, Chin-San, Wei, An-Chi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348158/
https://www.ncbi.nlm.nih.gov/pubmed/34360740
http://dx.doi.org/10.3390/ijms22157974