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Transcriptomic and Metabolic Network Analysis of Metabolic Reprogramming and IGF-1 Modulation in SCA3 Transgenic Mice
Spinocerebellar ataxia type 3 (SCA3) is a genetic neurodegenerative disease for which a cure is still needed. Growth hormone (GH) therapy has shown positive effects on the exercise behavior of mice with cerebellar atrophy, retains more Purkinje cells, and exhibits less DNA damage after GH interventi...
Autores principales: | Lin, Yu-Te, Lin, Yong-Shiou, Cheng, Wen-Ling, Chang, Jui-Chih, Chao, Yi-Chun, Liu, Chin-San, Wei, An-Chi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348158/ https://www.ncbi.nlm.nih.gov/pubmed/34360740 http://dx.doi.org/10.3390/ijms22157974 |
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