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Dosimetric Application of Phosphorus Doped Fibre for X-ray and Proton Therapy
Phosphorous-doped silica optical fibres with a core diameter of 4 µm were tested in X-ray and proton fields for application in cancer therapy dosimetry. Specifically, the radiation-induced attenuation was investigated in terms of linearity in deposited dose in 15 MV and 6 MV photons and 74 MeV proto...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348175/ https://www.ncbi.nlm.nih.gov/pubmed/34372394 http://dx.doi.org/10.3390/s21155157 |
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author | Olusoji, Olugbenga J. Penner, Crystal Bélanger-Champagne, Camille Kam, Wern Martyn, Michael Woulfe, Peter Hoehr, Cornelia O’Keeffe, Sinead |
author_facet | Olusoji, Olugbenga J. Penner, Crystal Bélanger-Champagne, Camille Kam, Wern Martyn, Michael Woulfe, Peter Hoehr, Cornelia O’Keeffe, Sinead |
author_sort | Olusoji, Olugbenga J. |
collection | PubMed |
description | Phosphorous-doped silica optical fibres with a core diameter of 4 µm were tested in X-ray and proton fields for application in cancer therapy dosimetry. Specifically, the radiation-induced attenuation was investigated in terms of linearity in deposited dose in 15 MV and 6 MV photons and 74 MeV protons, as well as Bragg-peak detection along the proton track. Fibres were found to demonstrate linear relative dose response in both radiation modalities, but possible saturation did occur at the high linear energy transfer of the Bragg peak. This demonstrates the possibility to use these fibres as a relative dosimeter for radiation therapy applications. |
format | Online Article Text |
id | pubmed-8348175 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-83481752021-08-08 Dosimetric Application of Phosphorus Doped Fibre for X-ray and Proton Therapy Olusoji, Olugbenga J. Penner, Crystal Bélanger-Champagne, Camille Kam, Wern Martyn, Michael Woulfe, Peter Hoehr, Cornelia O’Keeffe, Sinead Sensors (Basel) Communication Phosphorous-doped silica optical fibres with a core diameter of 4 µm were tested in X-ray and proton fields for application in cancer therapy dosimetry. Specifically, the radiation-induced attenuation was investigated in terms of linearity in deposited dose in 15 MV and 6 MV photons and 74 MeV protons, as well as Bragg-peak detection along the proton track. Fibres were found to demonstrate linear relative dose response in both radiation modalities, but possible saturation did occur at the high linear energy transfer of the Bragg peak. This demonstrates the possibility to use these fibres as a relative dosimeter for radiation therapy applications. MDPI 2021-07-30 /pmc/articles/PMC8348175/ /pubmed/34372394 http://dx.doi.org/10.3390/s21155157 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Communication Olusoji, Olugbenga J. Penner, Crystal Bélanger-Champagne, Camille Kam, Wern Martyn, Michael Woulfe, Peter Hoehr, Cornelia O’Keeffe, Sinead Dosimetric Application of Phosphorus Doped Fibre for X-ray and Proton Therapy |
title | Dosimetric Application of Phosphorus Doped Fibre for X-ray and Proton Therapy |
title_full | Dosimetric Application of Phosphorus Doped Fibre for X-ray and Proton Therapy |
title_fullStr | Dosimetric Application of Phosphorus Doped Fibre for X-ray and Proton Therapy |
title_full_unstemmed | Dosimetric Application of Phosphorus Doped Fibre for X-ray and Proton Therapy |
title_short | Dosimetric Application of Phosphorus Doped Fibre for X-ray and Proton Therapy |
title_sort | dosimetric application of phosphorus doped fibre for x-ray and proton therapy |
topic | Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348175/ https://www.ncbi.nlm.nih.gov/pubmed/34372394 http://dx.doi.org/10.3390/s21155157 |
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