Fatty Acid Synthesis in Glial Cells of the CNS

Fatty acids (FAs) are of crucial importance for brain homeostasis and neural function. Glia cells support the high demand of FAs that the central nervous system (CNS) needs for its proper functioning. Additionally, FAs can modulate inflammation and direct CNS repair, thereby contributing to brain pa...

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Autores principales: Garcia Corrales, Aida V., Haidar, Mansour, Bogie, Jeroen F. J., Hendriks, Jerome J. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348209/
https://www.ncbi.nlm.nih.gov/pubmed/34360931
http://dx.doi.org/10.3390/ijms22158159
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author Garcia Corrales, Aida V.
Haidar, Mansour
Bogie, Jeroen F. J.
Hendriks, Jerome J. A.
author_facet Garcia Corrales, Aida V.
Haidar, Mansour
Bogie, Jeroen F. J.
Hendriks, Jerome J. A.
author_sort Garcia Corrales, Aida V.
collection PubMed
description Fatty acids (FAs) are of crucial importance for brain homeostasis and neural function. Glia cells support the high demand of FAs that the central nervous system (CNS) needs for its proper functioning. Additionally, FAs can modulate inflammation and direct CNS repair, thereby contributing to brain pathologies such Alzheimer’s disease or multiple sclerosis. Intervention strategies targeting FA synthesis in glia represents a potential therapeutic opportunity for several CNS diseases.
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spelling pubmed-83482092021-08-08 Fatty Acid Synthesis in Glial Cells of the CNS Garcia Corrales, Aida V. Haidar, Mansour Bogie, Jeroen F. J. Hendriks, Jerome J. A. Int J Mol Sci Review Fatty acids (FAs) are of crucial importance for brain homeostasis and neural function. Glia cells support the high demand of FAs that the central nervous system (CNS) needs for its proper functioning. Additionally, FAs can modulate inflammation and direct CNS repair, thereby contributing to brain pathologies such Alzheimer’s disease or multiple sclerosis. Intervention strategies targeting FA synthesis in glia represents a potential therapeutic opportunity for several CNS diseases. MDPI 2021-07-29 /pmc/articles/PMC8348209/ /pubmed/34360931 http://dx.doi.org/10.3390/ijms22158159 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Garcia Corrales, Aida V.
Haidar, Mansour
Bogie, Jeroen F. J.
Hendriks, Jerome J. A.
Fatty Acid Synthesis in Glial Cells of the CNS
title Fatty Acid Synthesis in Glial Cells of the CNS
title_full Fatty Acid Synthesis in Glial Cells of the CNS
title_fullStr Fatty Acid Synthesis in Glial Cells of the CNS
title_full_unstemmed Fatty Acid Synthesis in Glial Cells of the CNS
title_short Fatty Acid Synthesis in Glial Cells of the CNS
title_sort fatty acid synthesis in glial cells of the cns
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348209/
https://www.ncbi.nlm.nih.gov/pubmed/34360931
http://dx.doi.org/10.3390/ijms22158159
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AT hendriksjeromeja fattyacidsynthesisinglialcellsofthecns

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