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Direct Measurement of the Affinity between tBid and Bax in a Mitochondria-Like Membrane

The execution step in apoptosis is the permeabilization of the outer mitochondrial membrane, controlled by Bcl-2 family proteins. The physical interactions between the different proteins in this family and their relative abundance literally determine the fate of the cells. These interactions, howeve...

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Detalles Bibliográficos
Autores principales: Rose, Markus, Kurylowicz, Martin, Mahmood, Mohammad, Winkel, Sheldon, Moran-Mirabal, Jose M., Fradin, Cécile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348223/
https://www.ncbi.nlm.nih.gov/pubmed/34361006
http://dx.doi.org/10.3390/ijms22158240