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Improving the Utility of a Dynorphin Peptide Analogue Using Mannosylated Glycoliposomes
Peptide therapeutics offer numerous advantages in the treatment of diseases and disorders of the central nervous system (CNS). However, they are not without limitations, especially in terms of their pharmacokinetics where their metabolic lability and low blood–brain barrier penetration hinder their...
Autores principales: | Lewicky, Jordan D., Fraleigh, Nya L., Martel, Alexandrine L., Nguyen, Thi M.-D., Schiller, Peter W., Mousavifar, Leila, Roy, René, Le, Anh Dzung, Funk, Douglas, Le, Hoang-Thanh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348236/ https://www.ncbi.nlm.nih.gov/pubmed/34360762 http://dx.doi.org/10.3390/ijms22157996 |
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