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Conformations of voltage-sensing domain III differentially define Na(V) channel closed- and open-state inactivation

Voltage-gated Na(+) (Na(V)) channels underlie the initiation and propagation of action potentials (APs). Rapid inactivation after Na(V) channel opening, known as open-state inactivation, plays a critical role in limiting the AP duration. However, Na(V) channel inactivation can also occur before open...

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Detalles Bibliográficos
Autores principales:	Angsutararux, Paweorn, Kang, Po Wei, Zhu, Wandi, Silva, Jonathan R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2021
Materias:	Hypothesis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348240/ https://www.ncbi.nlm.nih.gov/pubmed/34347027 http://dx.doi.org/10.1085/jgp.202112891

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