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Patterns of dyslipidemia amongst hypertensive patients in Abuja, North Central Nigeria

INTRODUCTION: dyslipidemia and hypertension are independent cardiovascular risk factors that are linked by insulin resistance and commonly coexist as components of the metabolic syndrome. The consequences of dyslipidaemic patterns includes high cardiovascular risk profile and sequalae. Data on lipid...

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Autores principales: Onyegbutulem, Henry Chijioke, Dogo, Dilli, Alu, Francis, Dankyau, Musa, Olorunfemi, David Samuel, Abdullahi, Faruk Mustapha, Akerele, Isaac Olubanji, Bala, Nafisah Ja'afar, Ibeabuchi, Ugo Nnenna, Mohammed, Maimuna Onyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The African Field Epidemiology Network 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348252/
https://www.ncbi.nlm.nih.gov/pubmed/34394802
http://dx.doi.org/10.11604/pamj.2021.39.11.28807
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author Onyegbutulem, Henry Chijioke
Dogo, Dilli
Alu, Francis
Dankyau, Musa
Olorunfemi, David Samuel
Abdullahi, Faruk Mustapha
Akerele, Isaac Olubanji
Bala, Nafisah Ja'afar
Ibeabuchi, Ugo Nnenna
Mohammed, Maimuna Onyi
author_facet Onyegbutulem, Henry Chijioke
Dogo, Dilli
Alu, Francis
Dankyau, Musa
Olorunfemi, David Samuel
Abdullahi, Faruk Mustapha
Akerele, Isaac Olubanji
Bala, Nafisah Ja'afar
Ibeabuchi, Ugo Nnenna
Mohammed, Maimuna Onyi
author_sort Onyegbutulem, Henry Chijioke
collection PubMed
description INTRODUCTION: dyslipidemia and hypertension are independent cardiovascular risk factors that are linked by insulin resistance and commonly coexist as components of the metabolic syndrome. The consequences of dyslipidaemic patterns includes high cardiovascular risk profile and sequalae. Data on lipid patterns amongst hypertensive patients in Abuja, a city with affluent pattern of life style and rising cardiovascular risk profile is very scanty or limited to just levels of total plasma cholesterol. This study was aimed at determining the pattern and frequencies of dyslipidaemic forms among hypertensive patients in Abuja. METHODS: this was a retrospective cohort study with the following data collected; socio-demographics, anthropometric measures and certain metabolic parameters from the new and old groups and analyzed using IBM SPSS Statistics, version 23. All decisions were made using the assymp. Two-sided Pearson χ2 probability. Quantitative variables were expressed as means and standard deviations. Qualitative variables were expressed as percentages. A p-value of ≤0.05 was set as significant. RESULTS: eight hundred and fifty eight (858) cases were enrolled for this study, 704 (82.1%) olds and 154 (17.9%) news. There were 251 (29.3%) males and 607 (70.7%) females. The means of the two groups were largely comparable. The commonest dyslipidaemic type was reduced High density lipoprotein, HDL (96.1%), followed by elevated low-density lipoprotein, LDL (78.6%), then, elevated total cholesterol, (62.3%) TCHOL and elevated triglycerides, TG 43.5%. CONCLUSION: dyslipidemic forms are very common among hypertensive patients in Abuja, Nigeria, particularly reduced HDL. Some observed associations include; middle age, female gender, middle/upper socio-economic classes, low levels of physical activity, overweight/obesity, dysglycaemia and long-standing hypertension.
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spelling pubmed-83482522021-08-13 Patterns of dyslipidemia amongst hypertensive patients in Abuja, North Central Nigeria Onyegbutulem, Henry Chijioke Dogo, Dilli Alu, Francis Dankyau, Musa Olorunfemi, David Samuel Abdullahi, Faruk Mustapha Akerele, Isaac Olubanji Bala, Nafisah Ja'afar Ibeabuchi, Ugo Nnenna Mohammed, Maimuna Onyi Pan Afr Med J Research INTRODUCTION: dyslipidemia and hypertension are independent cardiovascular risk factors that are linked by insulin resistance and commonly coexist as components of the metabolic syndrome. The consequences of dyslipidaemic patterns includes high cardiovascular risk profile and sequalae. Data on lipid patterns amongst hypertensive patients in Abuja, a city with affluent pattern of life style and rising cardiovascular risk profile is very scanty or limited to just levels of total plasma cholesterol. This study was aimed at determining the pattern and frequencies of dyslipidaemic forms among hypertensive patients in Abuja. METHODS: this was a retrospective cohort study with the following data collected; socio-demographics, anthropometric measures and certain metabolic parameters from the new and old groups and analyzed using IBM SPSS Statistics, version 23. All decisions were made using the assymp. Two-sided Pearson χ2 probability. Quantitative variables were expressed as means and standard deviations. Qualitative variables were expressed as percentages. A p-value of ≤0.05 was set as significant. RESULTS: eight hundred and fifty eight (858) cases were enrolled for this study, 704 (82.1%) olds and 154 (17.9%) news. There were 251 (29.3%) males and 607 (70.7%) females. The means of the two groups were largely comparable. The commonest dyslipidaemic type was reduced High density lipoprotein, HDL (96.1%), followed by elevated low-density lipoprotein, LDL (78.6%), then, elevated total cholesterol, (62.3%) TCHOL and elevated triglycerides, TG 43.5%. CONCLUSION: dyslipidemic forms are very common among hypertensive patients in Abuja, Nigeria, particularly reduced HDL. Some observed associations include; middle age, female gender, middle/upper socio-economic classes, low levels of physical activity, overweight/obesity, dysglycaemia and long-standing hypertension. The African Field Epidemiology Network 2021-05-04 /pmc/articles/PMC8348252/ /pubmed/34394802 http://dx.doi.org/10.11604/pamj.2021.39.11.28807 Text en Copyright: Henry Chijioke Onyegbutulem et al. https://creativecommons.org/licenses/by/4.0/The Pan African Medical Journal (ISSN: 1937-8688). This is an Open Access article distributed under the terms of the Creative Commons Attribution International 4.0 License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Onyegbutulem, Henry Chijioke
Dogo, Dilli
Alu, Francis
Dankyau, Musa
Olorunfemi, David Samuel
Abdullahi, Faruk Mustapha
Akerele, Isaac Olubanji
Bala, Nafisah Ja'afar
Ibeabuchi, Ugo Nnenna
Mohammed, Maimuna Onyi
Patterns of dyslipidemia amongst hypertensive patients in Abuja, North Central Nigeria
title Patterns of dyslipidemia amongst hypertensive patients in Abuja, North Central Nigeria
title_full Patterns of dyslipidemia amongst hypertensive patients in Abuja, North Central Nigeria
title_fullStr Patterns of dyslipidemia amongst hypertensive patients in Abuja, North Central Nigeria
title_full_unstemmed Patterns of dyslipidemia amongst hypertensive patients in Abuja, North Central Nigeria
title_short Patterns of dyslipidemia amongst hypertensive patients in Abuja, North Central Nigeria
title_sort patterns of dyslipidemia amongst hypertensive patients in abuja, north central nigeria
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348252/
https://www.ncbi.nlm.nih.gov/pubmed/34394802
http://dx.doi.org/10.11604/pamj.2021.39.11.28807
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