Pneumopathie infiltrante diffuse secondaire à un syndrome des antisynthétases: à propos d´un cas

Diffuse infiltrate lung diseases (DILDs) are frequent in patients with connective tissue diseases. They can be suggestive of connective tissue diseases or occur during follow-up. Antisynthetase syndrome (ASS) is a complex and heterogeneous connective tissue disease. Antisynthetase antibodies, in par...

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Detalles Bibliográficos
Autores principales: Moussa, Nadia, Khemakhem, Rim, Snoussi, Mouna, Fekih, Wafa, Bahloul, Zouhir, Kammoun, Sami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The African Field Epidemiology Network 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348253/
https://www.ncbi.nlm.nih.gov/pubmed/34394821
http://dx.doi.org/10.11604/pamj.2021.39.30.22654
Descripción
Sumario:Diffuse infiltrate lung diseases (DILDs) are frequent in patients with connective tissue diseases. They can be suggestive of connective tissue diseases or occur during follow-up. Antisynthetase syndrome (ASS) is a complex and heterogeneous connective tissue disease. Antisynthetase antibodies, in particular the anti-Jo1 antibody, are found in patients with this syndrome. The prognosis of ASS is conditioned by the occurrence of DILD and its severity, thus guiding therapeutic management. We here report the case of a 57-year-old female patient presenting with acute febrile DILD revealing ASS. Outcome was favorable under bolus corticosteroids in combination with cyclophosphamide treatment.

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