Pneumopathie infiltrante diffuse secondaire à un syndrome des antisynthétases: à propos d´un cas

Diffuse infiltrate lung diseases (DILDs) are frequent in patients with connective tissue diseases. They can be suggestive of connective tissue diseases or occur during follow-up. Antisynthetase syndrome (ASS) is a complex and heterogeneous connective tissue disease. Antisynthetase antibodies, in par...

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Autores principales: Moussa, Nadia, Khemakhem, Rim, Snoussi, Mouna, Fekih, Wafa, Bahloul, Zouhir, Kammoun, Sami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The African Field Epidemiology Network 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348253/
https://www.ncbi.nlm.nih.gov/pubmed/34394821
http://dx.doi.org/10.11604/pamj.2021.39.30.22654
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author Moussa, Nadia
Khemakhem, Rim
Snoussi, Mouna
Fekih, Wafa
Bahloul, Zouhir
Kammoun, Sami
author_facet Moussa, Nadia
Khemakhem, Rim
Snoussi, Mouna
Fekih, Wafa
Bahloul, Zouhir
Kammoun, Sami
author_sort Moussa, Nadia
collection PubMed
description Diffuse infiltrate lung diseases (DILDs) are frequent in patients with connective tissue diseases. They can be suggestive of connective tissue diseases or occur during follow-up. Antisynthetase syndrome (ASS) is a complex and heterogeneous connective tissue disease. Antisynthetase antibodies, in particular the anti-Jo1 antibody, are found in patients with this syndrome. The prognosis of ASS is conditioned by the occurrence of DILD and its severity, thus guiding therapeutic management. We here report the case of a 57-year-old female patient presenting with acute febrile DILD revealing ASS. Outcome was favorable under bolus corticosteroids in combination with cyclophosphamide treatment.
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spelling pubmed-83482532021-08-13 Pneumopathie infiltrante diffuse secondaire à un syndrome des antisynthétases: à propos d´un cas Moussa, Nadia Khemakhem, Rim Snoussi, Mouna Fekih, Wafa Bahloul, Zouhir Kammoun, Sami Pan Afr Med J Case Report Diffuse infiltrate lung diseases (DILDs) are frequent in patients with connective tissue diseases. They can be suggestive of connective tissue diseases or occur during follow-up. Antisynthetase syndrome (ASS) is a complex and heterogeneous connective tissue disease. Antisynthetase antibodies, in particular the anti-Jo1 antibody, are found in patients with this syndrome. The prognosis of ASS is conditioned by the occurrence of DILD and its severity, thus guiding therapeutic management. We here report the case of a 57-year-old female patient presenting with acute febrile DILD revealing ASS. Outcome was favorable under bolus corticosteroids in combination with cyclophosphamide treatment. The African Field Epidemiology Network 2021-05-11 /pmc/articles/PMC8348253/ /pubmed/34394821 http://dx.doi.org/10.11604/pamj.2021.39.30.22654 Text en Copyright: Nadia Moussa et al. https://creativecommons.org/licenses/by/4.0/The Pan African Medical Journal (ISSN: 1937-8688). This is an Open Access article distributed under the terms of the Creative Commons Attribution International 4.0 License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Moussa, Nadia
Khemakhem, Rim
Snoussi, Mouna
Fekih, Wafa
Bahloul, Zouhir
Kammoun, Sami
Pneumopathie infiltrante diffuse secondaire à un syndrome des antisynthétases: à propos d´un cas
title Pneumopathie infiltrante diffuse secondaire à un syndrome des antisynthétases: à propos d´un cas
title_full Pneumopathie infiltrante diffuse secondaire à un syndrome des antisynthétases: à propos d´un cas
title_fullStr Pneumopathie infiltrante diffuse secondaire à un syndrome des antisynthétases: à propos d´un cas
title_full_unstemmed Pneumopathie infiltrante diffuse secondaire à un syndrome des antisynthétases: à propos d´un cas
title_short Pneumopathie infiltrante diffuse secondaire à un syndrome des antisynthétases: à propos d´un cas
title_sort pneumopathie infiltrante diffuse secondaire à un syndrome des antisynthétases: à propos d´un cas
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348253/
https://www.ncbi.nlm.nih.gov/pubmed/34394821
http://dx.doi.org/10.11604/pamj.2021.39.30.22654
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