Cargando…

Lip and oral cavity cancers (C00-C06) from a mega city of Pakistan: Ten-year data from the Dow Cancer Registry

OBJECTIVE: The objective of this report is to provide an overview of lip and oral cavity cancer in Karachi, the largest city in Pakistan. METHODS: This study was undertaken at the Dow Cancer Registry. During 2010–2019, all patients who were residents of Karachi who had been diagnosed with lip and or...

Descripción completa

Detalles Bibliográficos
Autores principales: Qureshi, Muhammad A., Syed, Sofia Ali, Sharafat, Shaheen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taibah University 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348287/
https://www.ncbi.nlm.nih.gov/pubmed/34408617
http://dx.doi.org/10.1016/j.jtumed.2021.02.001
_version_ 1783735302792151040
author Qureshi, Muhammad A.
Syed, Sofia Ali
Sharafat, Shaheen
author_facet Qureshi, Muhammad A.
Syed, Sofia Ali
Sharafat, Shaheen
author_sort Qureshi, Muhammad A.
collection PubMed
description OBJECTIVE: The objective of this report is to provide an overview of lip and oral cavity cancer in Karachi, the largest city in Pakistan. METHODS: This study was undertaken at the Dow Cancer Registry. During 2010–2019, all patients who were residents of Karachi who had been diagnosed with lip and oral cavity cancer were registered and recruited for this study. The data were entered in SPSS and MS Excel sheets to investigate frequencies, age-standardized-rates (ASR) and other clinicopathological parameters. The data from our study were compared with the ASR of lip and oral cavity cancer from selected Asian countries. RESULTS: During the defined period, 22,858 cancer cases were registered. Of these, 4,400 (19.2%, ASR 28.0) were lip and oral cavity cancer (the most common type found in males and the second most common type in females), of which 2,986 (67.8%) were found in males, while 1,414 (32.1%) were reported in females. Squamous cell carcinoma was the most common type (97.7%). Most tumours were moderately differentiated (67.7%) followed by poorly (16.6%), and well differentiated (15.7%). CONCLUSION: We report an alarmingly high ASR of lip and oral cavity cancer in Karachi as compared to Pakistan as a whole and other Asian countries.
format Online
Article
Text
id pubmed-8348287
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Taibah University
record_format MEDLINE/PubMed
spelling pubmed-83482872021-08-17 Lip and oral cavity cancers (C00-C06) from a mega city of Pakistan: Ten-year data from the Dow Cancer Registry Qureshi, Muhammad A. Syed, Sofia Ali Sharafat, Shaheen J Taibah Univ Med Sci Brief Communication OBJECTIVE: The objective of this report is to provide an overview of lip and oral cavity cancer in Karachi, the largest city in Pakistan. METHODS: This study was undertaken at the Dow Cancer Registry. During 2010–2019, all patients who were residents of Karachi who had been diagnosed with lip and oral cavity cancer were registered and recruited for this study. The data were entered in SPSS and MS Excel sheets to investigate frequencies, age-standardized-rates (ASR) and other clinicopathological parameters. The data from our study were compared with the ASR of lip and oral cavity cancer from selected Asian countries. RESULTS: During the defined period, 22,858 cancer cases were registered. Of these, 4,400 (19.2%, ASR 28.0) were lip and oral cavity cancer (the most common type found in males and the second most common type in females), of which 2,986 (67.8%) were found in males, while 1,414 (32.1%) were reported in females. Squamous cell carcinoma was the most common type (97.7%). Most tumours were moderately differentiated (67.7%) followed by poorly (16.6%), and well differentiated (15.7%). CONCLUSION: We report an alarmingly high ASR of lip and oral cavity cancer in Karachi as compared to Pakistan as a whole and other Asian countries. Taibah University 2021-03-04 /pmc/articles/PMC8348287/ /pubmed/34408617 http://dx.doi.org/10.1016/j.jtumed.2021.02.001 Text en © 2021 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Brief Communication
Qureshi, Muhammad A.
Syed, Sofia Ali
Sharafat, Shaheen
Lip and oral cavity cancers (C00-C06) from a mega city of Pakistan: Ten-year data from the Dow Cancer Registry
title Lip and oral cavity cancers (C00-C06) from a mega city of Pakistan: Ten-year data from the Dow Cancer Registry
title_full Lip and oral cavity cancers (C00-C06) from a mega city of Pakistan: Ten-year data from the Dow Cancer Registry
title_fullStr Lip and oral cavity cancers (C00-C06) from a mega city of Pakistan: Ten-year data from the Dow Cancer Registry
title_full_unstemmed Lip and oral cavity cancers (C00-C06) from a mega city of Pakistan: Ten-year data from the Dow Cancer Registry
title_short Lip and oral cavity cancers (C00-C06) from a mega city of Pakistan: Ten-year data from the Dow Cancer Registry
title_sort lip and oral cavity cancers (c00-c06) from a mega city of pakistan: ten-year data from the dow cancer registry
topic Brief Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348287/
https://www.ncbi.nlm.nih.gov/pubmed/34408617
http://dx.doi.org/10.1016/j.jtumed.2021.02.001
work_keys_str_mv AT qureshimuhammada lipandoralcavitycancersc00c06fromamegacityofpakistantenyeardatafromthedowcancerregistry
AT syedsofiaali lipandoralcavitycancersc00c06fromamegacityofpakistantenyeardatafromthedowcancerregistry
AT sharafatshaheen lipandoralcavitycancersc00c06fromamegacityofpakistantenyeardatafromthedowcancerregistry