Revisiting the Proposition of Binding Pockets and Bioactive Poses for GSK-3β Allosteric Modulators Addressed to Neurodegenerative Diseases

Glycogen synthase kinase-3 beta (GSK-3β) is an enzyme pertinently linked to neurodegenerative diseases since it is associated with the regulation of key neuropathological features in the central nervous system. Among the different kinds of inhibitors of this kinase, the allosteric ones stand out due...

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Detalles Bibliográficos
Autores principales: Silva, Guilherme M., Borges, Rosivaldo S., Santos, Kelton L. B., Federico, Leonardo B., Francischini, Isaque A. G., Gomes, Suzane Q., Barcelos, Mariana P., Silva, Rai C., Santos, Cleydson B. R., Silva, Carlos H. T. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348340/
https://www.ncbi.nlm.nih.gov/pubmed/34361017
http://dx.doi.org/10.3390/ijms22158252

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