Cargando…

Trans-(−)-Kusunokinin: A Potential Anticancer Lignan Compound against HER2 in Breast Cancer Cell Lines?

Trans-(−)-kusunokinin, an anticancer compound, binds CSF1R with low affinity in breast cancer cells. Therefore, finding an additional possible target of trans-(−)-kusunokinin remains of importance for further development. Here, a computational study was completed followed by indirect proof of specif...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rattanaburee, Thidarath, Tanawattanasuntorn, Tanotnon, Thongpanchang, Tienthong, Tipmanee, Varomyalin, Graidist, Potchanapond
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348432/ https://www.ncbi.nlm.nih.gov/pubmed/34361688 http://dx.doi.org/10.3390/molecules26154537

Ejemplares similares

Trans-(±)-Kusunokinin Binding to AKR1B1 Inhibits Oxidative Stress and Proteins Involved in Migration in Aggressive Breast Cancer
por: Tanawattanasuntorn, Tanotnon, et al.
Publicado: (2022)

Effects of trans-(±)-kusunokinin on chemosensitive and chemoresistant ovarian cancer cells
por: Mad-Adam, Nadeeya, et al.
Publicado: (2022)

(−)-Kusunokinin as a Potential Aldose Reductase Inhibitor: Equivalency Observed via AKR1B1 Dynamics Simulation
por: Tanawattanasuntorn, Tanotnon, et al.
Publicado: (2020)

Anticancer Activity of (±)-Kusunokinin Derivatives towards Cholangiocarcinoma Cells
por: Rattanaburee, Thidarath, et al.
Publicado: (2022)

Trans-(±)-TTPG-B Attenuates Cell Cycle Progression and Inhibits Cell Proliferation on Cholangiocarcinoma Cells
por: Rattanaburee, Thidarath, et al.
Publicado: (2023)

Potential Stereoselective Binding of Trans-(±)-Kusunokinin and Cis-(±)-Kusunokinin Isomers to CSF1R
por: Chompunud Na Ayudhya, Chompunud, et al.
Publicado: (2022)

Cytotoxic Activity of Piper cubeba Extract in Breast Cancer Cell Lines
por: Graidist, Potchanapond, et al.
Publicado: (2015)

Novel Compound Heterozygous Mutations in the TRAPPC9 Gene in Two Siblings With Autism and Intellectual Disability
por: Hnoonual, Areerat, et al.
Publicado: (2019)

Anti-Proliferative Effects of Compound A and Its Effect in Combination with Cisplatin in Cholangiocarcinoma Cells
por: Junking, Mutita, et al.
Publicado: (2020)

Anticancer Effects and Molecular Action of 7-α-Hydroxyfrullanolide in G2/M-Phase Arrest and Apoptosis in Triple Negative Breast Cancer Cells
por: Chimplee, Siriphorn, et al.
Publicado: (2022)

Anticancer mechanism of 7-α-hydroxyfrullanolide on microtubules and computational prediction of its target binding in triple-negative breast cancer cells
por: Chimplee, Siriphorn, et al.
Publicado: (2022)

Extracts from Vatica diospyroides Type SS Fruit Show Low Dose Activity against MDA-MB-468 Breast Cancer Cell-Line via Apoptotic Action
por: Srisawat, Theera, et al.
Publicado: (2014)

The dose dependent in vitro responses of MCF-7 and MDA-MB-231 cell lines to extracts of Vatica diospyroides symington type SS fruit include effects on mode of cell death
por: Srisawat, Theera, et al.
Publicado: (2015)

Lignans: a versatile source of anticancer drugs
por: Mukhija, Minky, et al.
Publicado: (2022)

In Silico Prediction of Cross-Reactive Epitopes of Tropomyosin from Shrimp and Other Arthropods Involved in Allergy
por: Saetang, Jirakrit, et al.
Publicado: (2022)

Anticancer Potentials of the Lignan Magnolin: A Systematic Review
por: Bhuia, Md. Shimul, et al.
Publicado: (2023)

In Silico Identification of Potential Sites for a Plastic-Degrading Enzyme by a Reverse Screening through the Protein Sequence Space and Molecular Dynamics Simulations
por: Charupanit, Krit, et al.
Publicado: (2022)

Piper nigrum Extract: Dietary Supplement for Reducing Mammary Tumor Incidence and Chemotherapy-Induced Toxicity
por: Mad-adam, Nadeeya, et al.
Publicado: (2023)

Anticancer potentiality of lignan rich fraction of six Flaxseed cultivars
por: Ezzat, Shahira M., et al.
Publicado: (2018)

Effects of Astaxanthin from Litopenaeus Vannamei on Carrageenan-Induced Edema and Pain Behavior in Mice
por: Kuedo, Zulkiflee, et al.
Publicado: (2016)

HLA-B*15:21 and carbamazepine-induced Stevens-Johnson syndrome: pooled-data and in silico analysis
por: Jaruthamsophon, Kanoot, et al.
Publicado: (2017)

Novel Lawsone–Quinoxaline Hybrids as New Dual Binding Site Acetylcholinesterase Inhibitors
por: Suwanhom, Paptawan, et al.
Publicado: (2023)

Lignans
por: Barker, David
Publicado: (2019)

Molecular dynamic simulation of mutated β-catenin in solid pseudopapillary neoplasia of the pancreas
por: Tipmanee, Varomyalin, et al.
Publicado: (2018)

Senescence Process in Primary Wilms' Tumor Cell Culture Induced by p53 Independent p21 Expression
por: Theerakitthanakul, Korkiat, et al.
Publicado: (2016)

Ethnomedicinal, Phytochemical and Pharmacological Profile of Anthriscus sylvestris as an Alternative Source for Anticancer Lignans
por: Olaru, Octavian Tudorel, et al.
Publicado: (2015)

Virtual Screening of Different Subclasses of Lignans with Anticancer Potential and Based on Genetic Profile
por: Maia, Mayara dos Santos, et al.
Publicado: (2023)

A Role of Newly Found Auxiliary Site in Phospholipase A(1) from Thai Banded Tiger Wasp (Vespa affinis) in Its Enzymatic Enhancement: In Silico Homology Modeling and Molecular Dynamics Insights
por: Teajaroen, Withan, et al.
Publicado: (2020)

Metformin Inhibit Cervical Cancer Migration by Suppressing the FAK/Akt Signaling Pathway
por: Hakimee, Henna, et al.
Publicado: (2019)

Synthesis, Biological Evaluation, and In Silico Studies of New Acetylcholinesterase Inhibitors Based on Quinoxaline Scaffold
por: Suwanhom, Paptawan, et al.
Publicado: (2021)

Computational discovery of binding mode of anti-TRBC1 antibody and predicted key amino acids of TRBC1
por: Saetang, Jirakrit, et al.
Publicado: (2022)

Investigation of Linum flavum (L.) Hairy Root Cultures for the Production of Anticancer Aryltetralin Lignans
por: Renouard, Sullivan, et al.
Publicado: (2018)

Immunologic Function and Molecular Insight of Recombinant Interleukin-18
por: Saetang, Jirakrit, et al.
Publicado: (2016)

Computational model for lipid binding regions in phospholipase (Ves a 1) from Vespa venom
por: Pattaranggoon, Nawanwat C., et al.
Publicado: (2023)

The attenuation effect of low piperine Piper nigrum extract on doxorubicin-induced toxicity of blood chemical and immunological properties in mammary tumour rats
por: Saetang, Jirakrit, et al.
Publicado: (2021)

Modulation of Chloride Channel Functions by the Plant Lignan Compounds Kobusin and Eudesmin
por: Jiang, Yu, et al.
Publicado: (2015)

Effects of rhodomyrtone on Gram-positive bacterial tubulin homologue FtsZ
por: Saeloh, Dennapa, et al.
Publicado: (2017)

Astaxanthin induces migration in human skin keratinocytes via Rac1 activation and RhoA inhibition
por: Ritto, Dakanda, et al.
Publicado: (2017)

Oxidative Transformations of Lignans
por: Runeberg, Patrik A., et al.
Publicado: (2019)

NMR Characterization of Lignans
por: Consonni, Roberto, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_n8cc0udhvo2lh9equ37ju3vk6k