Cargando…

Hispolon Induces Apoptosis, Suppresses Migration and Invasion of Glioblastoma Cells and Inhibits GBM Xenograft Tumor Growth In Vivo

Hispolon, a polyphenol compound isolated from Phellinus linteus, has been reported to exhibit antioxidant, antiproliferative, and antitumor activities. This study aimed to explore the antitumor effects of hispolon on glioblastoma multiforme (GBM) cells in vitro and in vivo. The results revealed that...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liao, Kuan-Fu, Chiu, Tsung-Lang, Chang, Shu-Fang, Wang, Mei-Jen, Chiu, Sheng-Chun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348445/ https://www.ncbi.nlm.nih.gov/pubmed/34361649 http://dx.doi.org/10.3390/molecules26154497

Ejemplares similares

Demethoxycurcumin Suppresses Human Brain Glioblastoma Multiforme GBM 8401 Cell Xenograft Tumor in Nude Mice In Vivo
por: Huang, Yi-Ping, et al.
Publicado: (2021)

Tetrandrine Suppresses Human Brain Glioblastoma GBM 8401/luc2 Cell-Xenografted Subcutaneous Tumors in Nude Mice In Vivo
por: Liao, Ching-Lung, et al.
Publicado: (2021)

Hispolon Methyl Ether, a Hispolon Analog, Suppresses the SRC/STAT3/Survivin Signaling Axis to Induce Cytotoxicity in Human Urinary Bladder Transitional Carcinoma Cell Lines
por: Kuo, Min-Yung, et al.
Publicado: (2022)

Bisdemethoxycurcumin Induces Cell Apoptosis and Inhibits Human Brain Glioblastoma GBM 8401/Luc2 Cell Xenograft Tumor in Subcutaneous Nude Mice In Vivo
por: Hsia, Te-Chun, et al.
Publicado: (2022)

Analgesic Effects and the Mechanisms of Anti-Inflammation of Hispolon in Mice
por: Chang, Heng-Yuan, et al.
Publicado: (2011)

Zerumbone suppresses IKKα, Akt, and FOXO1 activation, resulting in apoptosis of GBM 8401 cells
por: Weng, Hsing-Yu, et al.
Publicado: (2012)

Hispolon suppresses metastasis via autophagic degradation of cathepsin S in cervical cancer cells
por: Hsin, Min-Chieh, et al.
Publicado: (2017)

Migration-Associated Transportome and Therapeutic Potential in Glioblastoma Multiforme (GBM)
por: Vaid, Samir, et al.
Publicado: (2023)

Hispolon induces apoptosis in oral squamous cell carcinoma cells through JNK/HO‐1 pathway activation
por: Yang, Wei‐En, et al.
Publicado: (2023)

Targeting the Axl and mTOR Pathway Synergizes Immunotherapy and Chemotherapy to Butylidenephthalide in a Recurrent GBM
por: Liu, Ching-Ann, et al.
Publicado: (2022)

Saponin 1 Induces Apoptosis and Suppresses NF-κB-Mediated Survival Signaling in Glioblastoma Multiforme (GBM)
por: Li, Juan, et al.
Publicado: (2013)

Mitochondrial DNA Alterations in Glioblastoma (GBM)
por: Leão Barros, Mariceli Baia, et al.
Publicado: (2021)

Correction: Saponin 1 Induces Apoptosis and Suppresses NF-κB-Mediated Survival Signaling in Glioblastoma Multiforme (GBM)
por: Li, Juan, et al.
Publicado: (2014)

Differences in creep response of GBM cells migrating in confinement
por: Khan, Ishan, et al.
Publicado: (2020)

Establishment and Biological Characterization of a Panel of Glioblastoma Multiforme (GBM) and GBM Variant Oncosphere Cell Lines
por: Binder, Zev A., et al.
Publicado: (2016)

Hispolon Cyclodextrin Complexes and Their Inclusion in Liposomes for Enhanced Delivery in Melanoma Cell Lines
por: Poudel, Ishwor, et al.
Publicado: (2022)

Hispolon Decreases Melanin Production and Induces Apoptosis in Melanoma Cells through the Downregulation of Tyrosinase and Microphthalmia-Associated Transcription Factor (MITF) Expressions and the Activation of Caspase-3, -8 and -9
por: Chen, Yi-Shyan, et al.
Publicado: (2014)

Using Light for Therapy of Glioblastoma Multiforme (GBM)
por: Vasilev, Alex, et al.
Publicado: (2020)

FAM72, Glioblastoma Multiforme (GBM) and Beyond
por: Ho, Nguyen Thi Thanh, et al.
Publicado: (2021)

Coactosin-Like Protein (COTL1) Promotes Glioblastoma (GBM) Growth in vitro and in vivo
por: Shao, Shike, et al.
Publicado: (2020)

Hispolon Protects against Acute Liver Damage in the Rat by Inhibiting Lipid Peroxidation, Proinflammatory Cytokine, and Oxidative Stress and Downregulating the Expressions of iNOS, COX-2, and MMP-9
por: Huang, Guan-Jhong, et al.
Publicado: (2012)

Hispolon: A natural polyphenol and emerging cancer killer by multiple cellular signaling pathways
por: Sarfraz, Ayesha, et al.
Publicado: (2020)

Involvement of Up-regulation of Death Receptors and Bim in Hispolon-mediated TNF-related Apoptosis-inducing Ligand Sensitization in Human Renal Carcinoma
por: Yun, Jung Mi, et al.
Publicado: (2019)

Dehydroxyhispolon Methyl Ether, A Hispolon Derivative, Inhibits WNT/β-Catenin Signaling to Elicit Human Colorectal Carcinoma Cell Apoptosis
por: Fan, Hueng-Chuen, et al.
Publicado: (2020)

Visualizing Molecular Profiles of Glioblastoma with GBM-BioDP
por: Celiku, Orieta, et al.
Publicado: (2014)

Prostate Apoptosis Response-4 (Par-4): A Novel Target in Pyronaridine-Induced Apoptosis in Glioblastoma (GBM) Cells
por: Ghosalkar, Jeevan, et al.
Publicado: (2022)

Phytosomal curcumin causes natural killer cell-dependent repolarization of glioblastoma (GBM) tumor-associated microglia/macrophages and elimination of GBM and GBM stem cells
por: Mukherjee, Sumit, et al.
Publicado: (2018)

The effect of silver nanoparticles (AgNPs) on proliferation and apoptosis of in ovo cultured glioblastoma multiforme (GBM) cells
por: Urbańska, Kaja, et al.
Publicado: (2015)

OKN-007 Increases temozolomide (TMZ) Sensitivity and Suppresses TMZ-Resistant Glioblastoma (GBM) Tumor Growth()()
por: Towner, Rheal A., et al.
Publicado: (2018)

Quantitative Magnetization Transfer in Monitoring Glioblastoma (GBM) Response to Therapy
por: Mehrabian, Hatef, et al.
Publicado: (2018)

Mechanisms of Resistance and Current Treatment Options for Glioblastoma Multiforme (GBM)
por: Yalamarty, Satya Siva Kishan, et al.
Publicado: (2023)

MOB2 suppresses GBM cell migration and invasion via regulation of FAK/Akt and cAMP/PKA signaling
por: Jiang, Ke, et al.
Publicado: (2020)

Toxicity and Antigenotoxic Effect of Hispolon Derivatives: Role of Structure in Modulating Cellular Redox State and Thioredoxin Reductase
por: Chethna, Pogakula, et al.
Publicado: (2018)

Application of Electric Cell-Substrate Impedance Sensing to Investigate the Cytotoxic Effects of Andrographolide on U-87 MG Glioblastoma Cell Migration and Apoptosis
por: Chiu, Sheng-Po, et al.
Publicado: (2019)

Methoxyhispolon Methyl Ether, a Hispolon Analog, Thwarts the SRC/STAT3/BCL-2 Axis to Provoke Human Triple-Negative Breast Cancer Cell Apoptosis In Vitro
por: Liao, Chih-Pin, et al.
Publicado: (2023)

The treatment of glioblastoma multiforme through activation of microglia and TRAIL induced by rAAV2-mediated IL-12 in a syngeneic rat model
por: Chiu, Tsung-Lang, et al.
Publicado: (2012)

Quantitative in vivo bioluminescence imaging of orthotopic patient-derived glioblastoma xenografts
por: Koessinger, Anna L., et al.
Publicado: (2020)

Anti-GD2-ch14.18/CHO coated nanoparticles mediate glioblastoma (GBM)-specific delivery of the aromatase inhibitor, Letrozole, reducing proliferation, migration and chemoresistance in patient-derived GBM tumor cells
por: Tivnan, Amanda, et al.
Publicado: (2017)

Hispolon-Loaded Liquid Crystalline Nanoparticles: Development, Stability, In Vitro Delivery Profile, and Assessment of Hepatoprotective Activity in Hepatocellular Carcinoma
por: Ansari, Mohammad Javed, et al.
Publicado: (2022)

Immunomodulatory Effect of Hispolon on LPS-Induced RAW264.7 Cells and Mitogen/Alloantigen-Stimulated Spleen Lymphocytes of Mice
por: Lee, Eun Kyeong, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_i483mupov7lce3pikghgg26vpu