Interleukin-17 and Th17 Lymphocytes Directly Impair Motoneuron Survival of Wildtype and FUS-ALS Mutant Human iPSCs

Amyotrophic lateral sclerosis (ALS) is a progressive disease leading to the degeneration of motor neurons (MNs). Neuroinflammation is involved in the pathogenesis of ALS; however, interactions of specific immune cell types and MNs are not well studied. We recently found a shift toward T helper (Th)1...

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Detalles Bibliográficos
Autores principales: Jin, Mengmeng, Akgün, Katja, Ziemssen, Tjalf, Kipp, Markus, Günther, Rene, Hermann, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348495/
https://www.ncbi.nlm.nih.gov/pubmed/34360808
http://dx.doi.org/10.3390/ijms22158042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348495/
https://www.ncbi.nlm.nih.gov/pubmed/34360808
http://dx.doi.org/10.3390/ijms22158042

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