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Ocular Complications of Obstructive Sleep Apnea
Obstructive sleep apnea (OSA), the most common form of sleep-disordered breathing, is characterized by repetitive episodes of paused breathing during sleep, which in turn induces transient nocturnal hypoxia and hypercapnia. The high prevalence of OSA and its associated health consequences place a he...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348497/ https://www.ncbi.nlm.nih.gov/pubmed/34362205 http://dx.doi.org/10.3390/jcm10153422 |
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author | Liu, Pei-Kang Chiu, Tzu-Yu Wang, Nan-Kai Levi, Sarah R. Tsai, Ming-Ju |
author_facet | Liu, Pei-Kang Chiu, Tzu-Yu Wang, Nan-Kai Levi, Sarah R. Tsai, Ming-Ju |
author_sort | Liu, Pei-Kang |
collection | PubMed |
description | Obstructive sleep apnea (OSA), the most common form of sleep-disordered breathing, is characterized by repetitive episodes of paused breathing during sleep, which in turn induces transient nocturnal hypoxia and hypercapnia. The high prevalence of OSA and its associated health consequences place a heavy burden on the healthcare system. In particular, the consequent episodic oxygenic desaturation/reoxygenation series and arousals from sleep in patients with OSA have the potential to trigger oxidative stress, elevated systemic inflammatory responses, and autonomic dysfunction with sympathetic activation. Given these adverse side-effects, OSA is highly correlated to many eye diseases that are common in everyday ophthalmic practices. Some of these ocular consequences are reversible, but they may permanently threaten a patient’s vision if not treated appropriately. Here, this article seeks to review the ocular consequences and potential pathophysiologic associations in patients with OSA. Understanding these OSA-related eye diseases may help clinicians provide comprehensive care to their patients. |
format | Online Article Text |
id | pubmed-8348497 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-83484972021-08-08 Ocular Complications of Obstructive Sleep Apnea Liu, Pei-Kang Chiu, Tzu-Yu Wang, Nan-Kai Levi, Sarah R. Tsai, Ming-Ju J Clin Med Review Obstructive sleep apnea (OSA), the most common form of sleep-disordered breathing, is characterized by repetitive episodes of paused breathing during sleep, which in turn induces transient nocturnal hypoxia and hypercapnia. The high prevalence of OSA and its associated health consequences place a heavy burden on the healthcare system. In particular, the consequent episodic oxygenic desaturation/reoxygenation series and arousals from sleep in patients with OSA have the potential to trigger oxidative stress, elevated systemic inflammatory responses, and autonomic dysfunction with sympathetic activation. Given these adverse side-effects, OSA is highly correlated to many eye diseases that are common in everyday ophthalmic practices. Some of these ocular consequences are reversible, but they may permanently threaten a patient’s vision if not treated appropriately. Here, this article seeks to review the ocular consequences and potential pathophysiologic associations in patients with OSA. Understanding these OSA-related eye diseases may help clinicians provide comprehensive care to their patients. MDPI 2021-07-31 /pmc/articles/PMC8348497/ /pubmed/34362205 http://dx.doi.org/10.3390/jcm10153422 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Liu, Pei-Kang Chiu, Tzu-Yu Wang, Nan-Kai Levi, Sarah R. Tsai, Ming-Ju Ocular Complications of Obstructive Sleep Apnea |
title | Ocular Complications of Obstructive Sleep Apnea |
title_full | Ocular Complications of Obstructive Sleep Apnea |
title_fullStr | Ocular Complications of Obstructive Sleep Apnea |
title_full_unstemmed | Ocular Complications of Obstructive Sleep Apnea |
title_short | Ocular Complications of Obstructive Sleep Apnea |
title_sort | ocular complications of obstructive sleep apnea |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348497/ https://www.ncbi.nlm.nih.gov/pubmed/34362205 http://dx.doi.org/10.3390/jcm10153422 |
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