Activation of Muscle-Specific Kinase (MuSK) Reduces Neuromuscular Defects in the Delta7 Mouse Model of Spinal Muscular Atrophy (SMA)

Spinal muscular atrophy (SMA) is a motor neuron disease caused by insufficient levels of the survival motor neuron (SMN) protein. One of the most prominent pathological characteristics of SMA involves defects of the neuromuscular junction (NMJ), such as denervation and reduced clustering of acetylch...

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Detalles Bibliográficos
Autores principales: Feng, Zhihua, Lam, Steven, Tenn, Elena-Marie Sandino, Ghosh, Arundhati Sengupta, Cantor, Sarah, Zhang, Wei, Yen, Pei-Fen, Chen, Karen S., Burden, Steven, Paushkin, Sergey, Ayalon, Gai, Ko, Chien-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348537/
https://www.ncbi.nlm.nih.gov/pubmed/34360794
http://dx.doi.org/10.3390/ijms22158015

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