Cargando…
Potential Assessment of UGT2B17 Inhibition by Salicylic Acid in Human Supersomes In Vitro
Glucuronidation is a Phase 2 metabolic pathway responsible for the metabolism and excretion of testosterone to a conjugate testosterone glucuronide. Bioavailability and the rate of anabolic steroid testosterone metabolism can be affected upon UGT glucuronidation enzyme alteration. However, there is...
Autores principales: | Salhab, Hassan, Naughton, Declan P., Barker, James |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348562/ https://www.ncbi.nlm.nih.gov/pubmed/34361561 http://dx.doi.org/10.3390/molecules26154410 |
Ejemplares similares
-
Red wine and component flavonoids inhibit UGT2B17 in vitro
por: Jenkinson, Carl, et al.
Publicado: (2012) -
Validation of an HPLC Method for the Simultaneous Quantification of Metabolic Reaction Products Catalysed by CYP2C11 Enzymes in Rat Liver Microsomes: In Vitro Inhibitory Effect of Salicylic Acid on CYP2C11 Enzyme
por: Salhab, Hassan, et al.
Publicado: (2019) -
Validation of an HPLC Method for the Simultaneous Quantification of Metabolic Reaction Products Catalysed by CYP2E1 Enzyme Activity: Inhibitory Effect of Cytochrome P450 Enzyme CYP2E1 by Salicylic Acid in Rat Liver Microsomes
por: Salhab, Hassan, et al.
Publicado: (2020) -
Development and Validation of an HPLC-UV Method for the Quantification of 4′-Hydroxydiclofenac Using Salicylic Acid: Future Applications for Measurement of In Vitro Drug–Drug Interaction in Rat Liver Microsomes
por: Salhab, Hassan, et al.
Publicado: (2022) -
Potentially harmful advantage to athletes: a putative connection between UGT2B17 gene deletion polymorphism and renal disorders with prolonged use of anabolic androgenic steroids
por: Deshmukh, Nawed, et al.
Publicado: (2010)