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Application of Modified mRNA in Somatic Reprogramming to Pluripotency and Directed Conversion of Cell Fate
Modified mRNA (modRNA)-based somatic reprogramming is an effective and safe approach that overcomes the genomic mutation risk caused by viral integrative methods. It has improved the disadvantages of conventional mRNA and has better stability and immunogenicity. The modRNA molecules encoding multipl...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348611/ https://www.ncbi.nlm.nih.gov/pubmed/34360910 http://dx.doi.org/10.3390/ijms22158148 |