Cargando…

Understanding Chronic Venous Disease: A Critical Overview of Its Pathophysiology and Medical Management

Chronic venous disease (CVD) is a multifactorial condition affecting an important percentage of the global population. It ranges from mild clinical signs, such as telangiectasias or reticular veins, to severe manifestations, such as venous ulcerations. However, varicose veins (VVs) are the most comm...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ortega, Miguel A., Fraile-Martínez, Oscar, García-Montero, Cielo, Álvarez-Mon, Miguel A., Chaowen, Chen, Ruiz-Grande, Fernando, Pekarek, Leonel, Monserrat, Jorge, Asúnsolo, Angel, García-Honduvilla, Natalio, Álvarez-Mon, Melchor, Bujan, Julia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348673/ https://www.ncbi.nlm.nih.gov/pubmed/34362022 http://dx.doi.org/10.3390/jcm10153239

Ejemplares similares

Tissue remodelling and increased DNA damage in patients with incompetent valves in chronic venous insufficiency
por: Ortega, Miguel A., et al.
Publicado: (2021)

Chronic venous disease patients show increased IRS-4 expression in the great saphenous vein wall
por: Ortega, Miguel A, et al.
Publicado: (2021)

Contribution of the Elastic Component and Venous Wall Arterialization in Patients with Venous Reflux
por: Ortega, Miguel A., et al.
Publicado: (2022)

Histopathological study of JNK in venous wall of patients with chronic venous insufficiency related to osteogenesis process
por: Ortega, Miguel A, et al.
Publicado: (2021)

Oxidative Stress Markers Are Associated with a Poor Prognosis in Patients with Pancreatic Cancer
por: Ortega, Miguel A., et al.
Publicado: (2022)

Increased Angiogenesis and Lymphangiogenesis in the Placental Villi of Women with Chronic Venous Disease during Pregnancy
por: Ortega, Miguel A, et al.
Publicado: (2020)

Implication of ERBB2 as a Predictive Tool for Survival in Patients with Pancreatic Cancer in Histological Studies
por: Ortega, Miguel A., et al.
Publicado: (2022)

Lipidomic profiling of chorionic villi in the placentas of women with chronic venous disease
por: Ortega, Miguel A, et al.
Publicado: (2020)

A General Overview on the Hyperbaric Oxygen Therapy: Applications, Mechanisms and Translational Opportunities
por: Ortega, Miguel A., et al.
Publicado: (2021)

Venous Wall of Patients with Chronic Venous Disease Exhibits a Glycolytic Phenotype
por: Fraile-Martinez, Oscar, et al.
Publicado: (2022)

Chronic Venous Disease Patients Showed Altered Expression of IGF-1/PAPP-A/STC-2 Axis in the Vein Wall
por: Ortega, Miguel A., et al.
Publicado: (2020)

An integrative look at SARS-CoV-2 (Review)
por: Ortega, Miguel A., et al.
Publicado: (2021)

Overexpression of glycolysis markers in placental tissue of pregnant women with chronic venous disease: a histological study
por: Ortega, Miguel A, et al.
Publicado: (2022)

Towards an updated view on the clinical management of pancreatic adenocarcinoma: Current and future perspectives
por: Pekarek, Leonel, et al.
Publicado: (2021)

Applications of Polymeric Composites in Bone Tissue Engineering and Jawbone Regeneration
por: Fraile-Martínez, Oscar, et al.
Publicado: (2021)

Physical Activity as an Imperative Support in Breast Cancer Management
por: Ortega, Miguel A., et al.
Publicado: (2020)

Nutritional Components in Western Diet Versus Mediterranean Diet at the Gut Microbiota–Immune System Interplay. Implications for Health and Disease
por: García-Montero, Cielo, et al.
Publicado: (2021)

A Review: Integrative Perspectives on the Features and Clinical Management of Psychotic Episodes in Pregnancy
por: Ortega, Miguel A., et al.
Publicado: (2023)

Association Between Lower Extremity Venous Insufficiency and Intrapartum Fetal Compromise: A Nationwide Cross-Sectional Study
por: Asúnsolo, Ángel, et al.
Publicado: (2021)

Chronic Venous Disease in Pregnant Women Causes an Increase in ILK in the Placental Villi Associated with a Decrease in E-Cadherin
por: Ortega, Miguel A., et al.
Publicado: (2022)

Clinical Applications of Classical and Novel Biological Markers of Pancreatic Cancer
por: Pekarek, Leonel, et al.
Publicado: (2022)

Newborns of Mothers with Venous Disease during Pregnancy Show Increased Levels of Lipid Peroxidation and Markers of Oxidative Stress and Hypoxia in the Umbilical Cord
por: Ortega, Miguel A., et al.
Publicado: (2021)

Clinical and Novel Biomarkers in Penile Carcinoma: A Prospective Review
por: Pekarek, Leonel, et al.
Publicado: (2022)

The Pivotal Role of the Placenta in Normal and Pathological Pregnancies: A Focus on Preeclampsia, Fetal Growth Restriction, and Maternal Chronic Venous Disease
por: Ortega, Miguel A., et al.
Publicado: (2022)

An increase in elastogenic components in the placental villi of women with chronic venous disease during pregnancy is associated with decreased EGFL7 expression level
por: Ortega, Miguel A., et al.
Publicado: (2021)

Type 2 Diabetes Mellitus Associated with Obesity (Diabesity). The Central Role of Gut Microbiota and Its Translational Applications
por: Ortega, Miguel A., et al.
Publicado: (2020)

Irregular Expression of Cellular Stress Response Markers in the Placenta of Women with Chronic Venous Disease
por: García-Montero, Cielo, et al.
Publicado: (2022)

Implication of the PI3K/Akt/mTOR Pathway in the Process of Incompetent Valves in Patients with Chronic Venous Insufficiency and the Relationship with Aging
por: Ortega, Miguel A., et al.
Publicado: (2018)

Exploring histopathological and serum biomarkers in lung adenocarcinoma: Clinical applications and translational opportunities (Review)
por: Ortega, Miguel A., et al.
Publicado: (2022)

Modification of the Polymer of a Bone Cement with Biodegradable Microspheres of PLGA and Loading with Daptomycin and Vancomycin Improve the Response to Bone Tissue Infection
por: García-García, Joaquin, et al.
Publicado: (2022)

The Regulatory Role of Mitochondrial MicroRNAs (MitomiRs) in Breast Cancer: Translational Implications Present and Future
por: Ortega, Miguel A., et al.
Publicado: (2020)

Upregulation of VEGF and PEDF in Placentas of Women with Lower Extremity Venous Insufficiency during Pregnancy and Its Implication in Villous Calcification
por: Ortega, Miguel A, et al.
Publicado: (2019)

Dendrimers and Dendritic Materials: From Laboratory to Medical Practice in Infectious Diseases
por: Ortega, Miguel Ángel, et al.
Publicado: (2020)

Update on uveal melanoma: Translational research from biology to clinical practice (Review)
por: Ortega, Miguel A., et al.
Publicado: (2020)

Abnormal proinflammatory and stressor environmental with increased the regulatory cellular IGF-1/PAPP-A/STC and Wnt-1/β-Catenin canonical pathway in placenta of women with Chronic venous Disease during Pregnancy
por: Ortega, Miguel A, et al.
Publicado: (2021)

An Updated Review of SARS-CoV-2 Vaccines and the Importance of Effective Vaccination Programs in Pandemic Times
por: García-Montero, Cielo, et al.
Publicado: (2021)

Pregnancy‐associated venous insufficiency course with placental and systemic oxidative stress
por: Ortega, Miguel A., et al.
Publicado: (2020)

Understanding the basis of major depressive disorder in oncological patients: Biological links, clinical management, challenges, and lifestyle medicine
por: Fraile-Martinez, Oscar, et al.
Publicado: (2022)

Chronic Venous Disease during Pregnancy Causes a Systematic Increase in Maternal and Fetal Proinflammatory Markers
por: Ortega, Miguel A., et al.
Publicado: (2022)

Unfolding the role of placental-derived Extracellular Vesicles in Pregnancy: From homeostasis to pathophysiology
por: Ortega, Miguel A., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_0bms6lrobmjm3l34ioo9jemfnh