Cargando…

Hinokitiol Exhibits Antitumor Properties through Induction of ROS-Mediated Apoptosis and p53-Driven Cell-Cycle Arrest in Endometrial Cancer Cell Lines (Ishikawa, HEC-1A, KLE)

Hinokitiol is a natural tropolone derivative that is present in the heartwood of cupressaceous plants, and has been extensively investigated for its anti-inflammatory, antioxidant, and antitumor properties in the context of various diseases. To date, the effects of hinokitiol on endometrial cancer (...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Hsin-Yuan, Cheng, Wen-Pin, Chiang, Yi-Fen, Hong, Yong-Han, Ali, Mohamed, Huang, Tsui-Chin, Wang, Kai-Lee, Shieh, Tzong-Ming, Chang, Hsin-Yi, Hsia, Shih-Min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348875/ https://www.ncbi.nlm.nih.gov/pubmed/34361036 http://dx.doi.org/10.3390/ijms22158268

Ejemplares similares

Determination of Heavy Metal Concentrations in Normal and Pathological Human Endometrial Biopsies and In Vitro Regulation of Gene Expression by Metals in the Ishikawa and Hec-1b Endometrial Cell Line
por: Guyot, Erwan, et al.
Publicado: (2015)

Boric Acid Exhibits Anticancer Properties in Human Endometrial Cancer Ishikawa Cells
por: Çakır Gündoğdu, Ayşe, et al.
Publicado: (2023)

LRIG2 is a growth suppressor of Hec-1A and Ishikawa endometrial adenocarcinoma cells by regulating PI3K/AKT- and EGFR-mediated apoptosis and cell-cycle
por: Suh, Dae-Shik, et al.
Publicado: (2018)

Isoliquiritigenin Reverses Epithelial-Mesenchymal Transition Through Modulation of the TGF-β/Smad Signaling Pathway in Endometrial Cancer
por: Chen, Hsin-Yuan, et al.
Publicado: (2021)

Evaluation Physical Characteristics and Comparison Antimicrobial and Anti-Inflammation Potentials of Dental Root Canal Sealers Containing Hinokitiol In Vitro
por: Shih, Yin-Hua, et al.
Publicado: (2014)

Induction of Apoptosis in Endometrial Cancer (Ishikawa) Cells by Pogostemon cablin Aqueous Extract (PCAE)
por: Tsai, Ching-Chou, et al.
Publicado: (2015)

Biological Activity of fac-[Re(CO)(3)(phen)(aspirin)], fac-[Re(CO)(3)(phen)(indomethacin)] and Their Original Counterparts against Ishikawa and HEC-1A Endometrial Cancer Cells
por: Kuźmycz, Olga, et al.
Publicado: (2022)

Rice Husk Silica Liquid Protects Pancreatic β Cells from Streptozotocin-Induced Oxidative Damage
por: Chen, Hsin-Yuan, et al.
Publicado: (2021)

Effects of Rice-Husk Silica Liquid in Streptozotocin-Induced Diabetic Mice
por: Chen, Hsin-Yuan, et al.
Publicado: (2022)

Quercetin Ameliorates Renal Injury and Pyroptosis in Lupus Nephritis through Inhibiting IL-33/ST2 Pathway In Vitro and In Vivo
por: Chen, Hsin-Yuan, et al.
Publicado: (2022)

Type II transmembrane serine proteases 4 (TMPRSS4) promotes proliferation, invasion and epithelial–mesenchymal transition in endometrial carcinoma cells (HEC1A and Ishikawa) via activation of MAPK and AKT
por: Xiao, Huan, et al.
Publicado: (2021)

Hinokitiol Inhibits Melanogenesis via AKT/mTOR Signaling in B16F10 Mouse Melanoma Cells
por: Tsao, Yu-Tzu, et al.
Publicado: (2016)

Isoliquiritigenin induces apoptosis and autophagy and inhibits endometrial cancer growth in mice
por: Wu, Chi-Hao, et al.
Publicado: (2016)

The Role of Cell Proliferation and Extracellular Matrix Accumulation Induced by Food Additive Butylated Hydroxytoluene in Uterine Leiomyoma
por: Chiang, Yi-Fen, et al.
Publicado: (2021)

Hinokitiol impedes tumor drug resistance by suppressing protein kinase B/mammalian targets of rapamycin axis
por: Ni, Ying-Jui, et al.
Publicado: (2022)

Genistein Disrupts Glucocorticoid Receptor Signaling in Human Uterine Endometrial Ishikawa Cells
por: Whirledge, Shannon, et al.
Publicado: (2014)

Autophagy inhibition augments resveratrol-induced apoptosis in Ishikawa endometrial cancer cells
por: Fukuda, Tomohiko, et al.
Publicado: (2016)

Protective Effects of Epigallocatechin Gallate (EGCG) on Endometrial, Breast, and Ovarian Cancers
por: Huang, Yun-Ju, et al.
Publicado: (2020)

Effect of Vitamin D Supplementation on Primary Dysmenorrhea: A Systematic Review and Meta-Analysis of Randomized Clinical Trials
por: Chen, Yi-Chun, et al.
Publicado: (2023)

Recent Advances in Glycyrrhiza glabra (Licorice)-Containing Herbs Alleviating Radiotherapy- and Chemotherapy-Induced Adverse Reactions in Cancer Treatment
por: Wang, Kai-Lee, et al.
Publicado: (2022)

Adlay Seed (Coix lacryma-jobi L. var. Ma-yuen Stapf.) Ethanolic Extract Fractions and Subfractions Induce Cell Cycle Arrest and Apoptosis in Human Breast and Cervical Cancer Cell Lines
por: Chiang, Yi-Fen, et al.
Publicado: (2022)

Protective Effects of Fucoxanthin on High Glucose- and 4-Hydroxynonenal (4-HNE)-Induced Injury in Human Retinal Pigment Epithelial Cells
por: Chiang, Yi-Fen, et al.
Publicado: (2020)

Estrogenicity of Glabridin in Ishikawa Cells
por: Su Wei Poh, Melissa, et al.
Publicado: (2015)

Protective Effects of Fucoxanthin on Hydrogen Peroxide-Induced Calcification of Heart Valve Interstitial Cells
por: Chiang, Yi-Fen, et al.
Publicado: (2021)

The Adipokine Visfatin Modulates Cancer Stem Cell Properties in Triple-Negative Breast Cancer
por: Chiang, Yi-Fen, et al.
Publicado: (2023)

Salvia sclarea L. Essential Oil Extract and Its Antioxidative Phytochemical Sclareol Inhibit Oxytocin-Induced Uterine Hypercontraction Dysmenorrhea Model by Inhibiting the Ca(2+)–MLCK–MLC20 Signaling Cascade: An Ex Vivo and In Vivo Study
por: Wong, Jennifer, et al.
Publicado: (2020)

Arrested cells are Mad as Hec
por: LeBrasseur, Nicole
Publicado: (2002)

Software tools for HEC applications
por: Fowler, R F, et al.
Publicado: (2003)

ATLAS HEC PHOTOS TRIUMF
Publicado: (1997)

Expression of CDK9 in endometrial cancer tissues and its effect on the proliferation of HEC-1B
por: Yang, Wen, et al.
Publicado: (2021)

Correction: Estrogenicity of Glabridin in Ishikawa Cells
por: Su Wei Poh, Melissa, et al.
Publicado: (2015)

Biological activity of the receptor for macrophage colony-stimulating factor in the human endometrial cancer cell line, Ishikawa.
por: Takeda, S., et al.
Publicado: (1996)

Combination of imatinib mesylate with lithium chloride and medroxyprogesterone acetate is highly active in Ishikawa endometrial carcinoma in vitro
por: Bilir, Ayhan, et al.
Publicado: (2011)

The characteristics of Ishikawa endometrial cancer cells are modified by substrate topography with cell-like features and the polymer surface
por: Tan, Li Hui, et al.
Publicado: (2015)

Expression of NR1H3 in endometrial carcinoma and its effect on the proliferation of Ishikawa cells in vitro
por: Fang, Fang, et al.
Publicado: (2019)

F-Spondin Is the Signal by Which 2-Methoxyestradiol Induces Apoptosis in the Endometrial Cancer Cell Line Ishikawa
por: Rincón-Rodriguez, Ramiro, et al.
Publicado: (2019)

Anti-Inflammatory and Anti-Hyperuricemic Effects of Chrysin on a High Fructose Corn Syrup-Induced Hyperuricemia Rat Model via the Amelioration of Urate Transporters and Inhibition of NLRP3 Inflammasome Signaling Pathway
por: Chang, Yi-Hsien, et al.
Publicado: (2021)

RNA interference-mediated targeting of DKK1 gene expression in Ishikawa endometrial carcinoma cells causes increased tumor cell invasion and migration
por: YI, NUO, et al.
Publicado: (2013)

Medroxyprogesterone Reverses Tolerable Dose Metformin-Induced Inhibition of Invasion via Matrix Metallopeptidase-9 and Transforming Growth Factor-β1 in KLE Endometrial Cancer Cells
por: Suh, Dong Hoon, et al.
Publicado: (2020)

Quercetin inhibits the progression of endometrial HEC-1-A cells by regulating ferroptosis—a preliminary study
por: Li, Xiaoqin, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_skkh7fbmqtflbmuhb3e918rknn